Results 291 to 300 of about 8,121,841 (424)

Molecular dynamics simulations of human cohesin subunits identify DNA binding sites and their potential roles in DNA loop extrusion. [PDF]

PLoS Comput Biol
Gu C, Takada S, Brandani GB, Terakawa T.
europepmc   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Roquin exhibits opposing effects on RNA stem-loop stability through its two ROQ domain binding sites. [PDF]

Proc Natl Acad Sci U S A
Tants JN, Walbrun A, Kollwitz L, Friedrich K, Rief M, Schlundt A.   +5 more
europepmc   +1 more source

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Nature Methods, 2013
Jason D. Buenrostro, P. Giresi, Lisa C. Zaba, Howard Y. Chang, W. Greenleaf   +4 more
semanticscholar   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Reducing off-target expression of mRNA therapeutics and vaccines in the liver with microRNA binding sites. [PDF]

Mol Ther Methods Clin Dev
Parrett BJ, Yamaoka S, Barry MA.
europepmc   +1 more source

Binding Site Determination from Kinetic Data

, 1971
Edward A. Meighen, J. Woodland Hastings
openalex   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity. [PDF]

Comput Struct Biotechnol J
Dashwood A, Makuyana N, van der Kant R, Ghodsinia A, Hernandez AR, Lienart S, Burton O, Dooley J, Ali M, Kouser L, Naranjo F, Holt MG, Rousseau F, Schymkowitz J, Liston A.   +14 more
europepmc   +1 more source

Dansylaziridine-labeled troponin C. A fluorescent probe of Ca2+ binding to the Ca2+-specific regulatory sites.

, 1978
J. David Johnson, John H. Collins, John D. Potter   +2 more
openalex   +1 more source