Results 291 to 300 of about 8,324,980 (383)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Mapping the Binding Sites of CA125-Specific Antibodies on a Revised Molecular Model of MUC16. [PDF]

Cancers (Basel)
Wang CW, Srivastava A, Hanson EK, McEntee CR, Nair T, March JC, Whelan RJ.   +6 more
europepmc   +1 more source

Location of Ribosomal Protein Binding Sites on 16S Ribosomal RNA

, 1972
Robert A. Zimmermann, Akira Muto, Peter Fellner, Chantal Ehresmann, Christiane Branlant   +4 more
openalex   +1 more source

Bridging lectin binding sites by multivalent carbohydrates.

Chemical Society Reviews, 2013
V. Wittmann, R. Pieters
semanticscholar   +1 more source

CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani, Tsuyoshi Nakai, Yasuhiro Maeda, Reiko Ohdake, Atsuhiro Higashi, Toshiki Maeda, Ryunosuke Nagao, Sayuri Shima, Kazuya Kawabata, Akihiro Ueda, Mizuki Ito, Hirohisa Watanabe   +11 more
wiley   +1 more source

Highly conserved ion binding sites are not all functionally relevant in mouse KCC4. [PDF]

Front Mol Biosci
Becker L, Hausmann J, Wellpott R, Hartmann AM.   +3 more
europepmc   +1 more source

Biosynthesis of bacterial glycogen. Isolation and characterization of the pyridoxal-P allosteric activator site and the ADP-glucose-protected pyridoxal-P binding site of Escherichia coli B ADP-glucose synthase

, 1978
Thomas F. Parsons, J. Preiss
openalex   +1 more source

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

Investigating and evaluating potential antigen binding sites for monoclonal anti-HER2 antibodies: The LightDock approach. [PDF]

Comput Struct Biotechnol J
Stefańczyk E, Mitura A, Utratna M, Staniszewska M.   +3 more
europepmc   +1 more source

Effect of estrogen on gene expression in the chick oviduct. V. Changes in the number of RNA polymerase binding and initiation sites in chromatin.

, 1975
Robert J. Schwartz, M-J Tsai, Sophia Y. Tsai, Bert W. O’Malley   +3 more
openalex   +1 more source