Results 81 to 90 of about 75,208 (292)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Tritordeum as an Innovative Alternative to Wheat: A Comparative Digestion Study on Bread

Molecules, 2022
Tritordeum results from the crossbreeding of a wild barley (Hordeum chilense) species with durum wheat (Triticum turgidum spp. turgidum). This hexaploid crop exhibits agronomic and rheological characteristics like soft wheat, resulting in an innovative ...
Chiara Nitride, Giovanni D’Auria, Andrea Dente, Viola Landolfi, Gianluca Picariello, Gianfranco Mamone, Massimo Blandino, Raffaele Romano, Pasquale Ferranti   +8 more
doaj   +1 more source

Influence of different soluble dietary fibers on the bioaccessibility of the minor Fusarium mycotoxin beauvericin [PDF]

, 2012
Beauvericin (BEA) is a bioactive compound produced by the secondary metabolism of several Fusarium strains and is known to have various biological activities.
Font G., Mañes J., Meca G., Meneghelli G., RITIENI, ALBERTO   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Effect on Selenium Concentrations of a Randomized Intervention with Fish and Mussels in a Population with Relatively Low Habitual Dietary Selenium Intake [PDF]

, 2015
Selenium status of the Danish population is below that assumed optimal for the suggested protective effects against chronic diseases, including certain cancers. Fish and shellfish are important dietary sources of selenium in Denmark.
Andersen, Klaus K., Christensen, Jane, Larsen, Erik Huusfeldt, Olsen, Anja, Outzen, Malene, Overvad, Kim, Tjønneland, Anne   +6 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Genotype and ripening method affect carotenoid content and bio-accessibility in banana

Food & Function
This study concludes that the genotype, ripening methods (natural vs. exogenous ethylene application), and carotenoid bioaccessible content should be considered when setting a nutrition goal for vitamin A biofortification in banana-breeding programs.
Bryan Munoz, Micaela Hayes, Penelope Perkins-Veazie, Nicholas Gillitt, Miguel Munoz, Colin D. Kay, Mary Ann Lila, Mario G. Ferruzzi, Massimo Iorizzo   +8 more
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Effects of Encapsulation and In Vitro Digestion on Anthocyanin Composition and Antioxidant Activity of Raspberry Juice Powder

Foods
Microbeads of raspberry extract were produced using encapsulation matrices alginate + pea protein isolate + psyllium mucilage, alginate + pea protein isolate + psyllium mucilage + okra, and alginate + pea protein isolate + psyllium mucilage + Aloe ferox ...
Mokgaetji Johanna Mokale, Sreejarani Kesavan Pillai, Dharini Sivakumar   +2 more
doaj   +1 more source

Does the source migration pathway of HBCDs to household dust influence their bioaccessibility? [PDF]

, 2016
A study was conducted to assess the human bioaccessibility of dust contaminated with hexabromocyclododecane (HBCD) via two migration pathways a) volatilisation with subsequent partitioning to dust particles, and b) abrasion of treated textile fibres ...
Abdallah, Abdallah, Ali, Allen, Bakker, Boutrup, Camenisch, Cassie Rauert, Chris D. Collins, Clausen, Collins, Covaci, Duggan, Duggan, EPA), U. S. E. P. A. U, Fang, Hamel, Jones-Otazo, Kajiwara, Keller, Oomen, Palace, Poster, Rauert, Rauert, Rauert, Roosens, Roze, Ruby, Ruby, Saegusa, Schreder, Schripp, Sonia García-Alcega, Stuart Harrad, Suzuki, Testa, U.S.EPA, U.S.EPA, U.S.EPA, Van de Wiele, Van den Eede, Webster, Weschler, Yamamoto, Yu, Yu, Yu, Zhang   +48 more
core   +1 more source