Results 81 to 90 of about 72,929 (276)

The Effect on Selenium Concentrations of a Randomized Intervention with Fish and Mussels in a Population with Relatively Low Habitual Dietary Selenium Intake [PDF]

, 2015
Selenium status of the Danish population is below that assumed optimal for the suggested protective effects against chronic diseases, including certain cancers. Fish and shellfish are important dietary sources of selenium in Denmark.
Andersen, Klaus K., Christensen, Jane, Larsen, Erik Huusfeldt, Olsen, Anja, Outzen, Malene, Overvad, Kim, Tjønneland, Anne   +6 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Simulated gastrointestinal digestion, intestinal permeation and plasma protein interaction of white, green, and black tea polyphenols [PDF]

, 2015
The gastrointestinal digestion, intestinal permeation, and plasma protein interaction of polyphenols from a single tea cultivar at different stages of processing (white, green, and black teas) were simulated.
Campiglia, Pietro, Giannetti, Daniela, Novellino, Ettore, Tenore, Gian Carlo   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Does the source migration pathway of HBCDs to household dust influence their bioaccessibility? [PDF]

, 2016
A study was conducted to assess the human bioaccessibility of dust contaminated with hexabromocyclododecane (HBCD) via two migration pathways a) volatilisation with subsequent partitioning to dust particles, and b) abrasion of treated textile fibres ...
Abdallah, Abdallah, Ali, Allen, Bakker, Boutrup, Camenisch, Cassie Rauert, Chris D. Collins, Clausen, Collins, Covaci, Duggan, Duggan, EPA), U. S. E. P. A. U, Fang, Hamel, Jones-Otazo, Kajiwara, Keller, Oomen, Palace, Poster, Rauert, Rauert, Rauert, Roosens, Roze, Ruby, Ruby, Saegusa, Schreder, Schripp, Sonia García-Alcega, Stuart Harrad, Suzuki, Testa, U.S.EPA, U.S.EPA, U.S.EPA, Van de Wiele, Van den Eede, Webster, Weschler, Yamamoto, Yu, Yu, Yu, Zhang   +48 more
core   +1 more source

Genotype and ripening method affect carotenoid content and bio-accessibility in banana

Food & Function
This study concludes that the genotype, ripening methods (natural vs. exogenous ethylene application), and carotenoid bioaccessible content should be considered when setting a nutrition goal for vitamin A biofortification in banana-breeding programs.
Bryan Munoz, Micaela Hayes, Penelope Perkins-Veazie, Nicholas Gillitt, Miguel Munoz, Colin D. Kay, Mary Ann Lila, Mario G. Ferruzzi, Massimo Iorizzo   +8 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effects of Encapsulation and In Vitro Digestion on Anthocyanin Composition and Antioxidant Activity of Raspberry Juice Powder

Foods
Microbeads of raspberry extract were produced using encapsulation matrices alginate + pea protein isolate + psyllium mucilage, alginate + pea protein isolate + psyllium mucilage + okra, and alginate + pea protein isolate + psyllium mucilage + Aloe ferox ...
Mokgaetji Johanna Mokale, Sreejarani Kesavan Pillai, Dharini Sivakumar   +2 more
doaj   +1 more source

Influence of different soluble dietary fibers on the bioaccessibility of the minor Fusarium mycotoxin beauvericin [PDF]

, 2012
Beauvericin (BEA) is a bioactive compound produced by the secondary metabolism of several Fusarium strains and is known to have various biological activities.
Font G., Mañes J., Meca G., Meneghelli G., RITIENI, ALBERTO   +4 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source