Results 51 to 60 of about 346,763 (316)

Opioids in COVID-19: Two Sides of a Coin

Frontiers in Pharmacology, 2022
Introduction: The treatment of most severe COVID-19 patients included the large-scale use of sedatives and analgesics–possibly in higher doses than usual–which was reported in the literature.
Camila Vantini Capasso Palamim, Camila Vantini Capasso Palamim, Matheus Negri Boschiero, Matheus Negri Boschiero, Aléthea Guimarães Faria, Aléthea Guimarães Faria, Felipe Eduardo Valencise, Felipe Eduardo Valencise, Fernando Augusto Lima Marson, Fernando Augusto Lima Marson   +9 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Comparison of the Contents of Bioactive Compounds and Quality Parameters in Selected Mango Cultivars

, 2013
Mango cultivars Tommy Atkins, Zill, Peach, Sabre, Rosa and Phiva were analyzed for their quality parameters (fruit weight, flesh color chroma, L, h0, total soluble solid [TSS]/titratable acidity [TA], firmness), bioactive compounds (total phenols ...
Gustavo Alberto Polenta, Dharini Sivakumar, Periyar Selvam Sellamuthu, Denoya, Gabriela Ines, Sivakumar, Dharini, Polenta, Gustavo Alberto, Puffy Soundy, Soundy, Puffy, Gabriela Inés Denoya, Sellamuthu, Periyar Selvam   +9 more
core   +1 more source

Bioactive Compounds from Gac (Momordica cochinchinensis Lour. Spreng)

, 2020
Cucurbits (gourds and cucumbers) are one of the most economically important plant families for food consumption globally. One specific representative, Momordica cochinchinensis, is geographically restricted to tropical Asia and contains the highest ...
Tien Huynh, Huynh, Tien T., Nguyen, Minh H. (R8307), Minh H. Nguyen   +3 more
core   +1 more source

Isolation and Genetic Identification of Endophytic Lactic Acid Bacteria From the Amazonian Açai Fruits: Probiotics Features of Selected Strains and Their Potential to Inhibit Pathogens

Frontiers in Microbiology, 2021
The açai palm (Euterpe oleracea) is native to the Amazon basin, a humid tropical forest. High levels of total mesophilic bacteria with high diversity have been consistently reported in açai fruits.
Suenne Taynah Abe Sato, Joana Montezano Marques, Joana Montezano Marques, André da Luz de Freitas, Raphaela Cristina Sanches Progênio, Márcio Roberto Teixeira Nunes, Janaína Mota de Vasconcelos Massafra, Fábio Gomes Moura, Hervé Rogez   +8 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Bioactive compounds, health benefits, and industrial applications of Tartary buckwheat (Fagopyrum tataricum)

, 2023
Tartary buckwheat belongs to the family Polygonaceae, which is a traditionally edible and medicinal plant. Due to its various bioactive compounds, the consumption of Tartary buckwheat is correlated to a wide range of health benefits, and increasing ...
Hu, Yichen, Carpena, Maria, Peng, Lianxin, Wang, Mingfu, Zhao, Jianglin, Garcia-Perez, Pascual, Cheng, Ka-Wing, Cao, Hui, Prieto, Miguel A., Ren, Guixing, Wu, Dingtao, Rengasamy, Kannan R. R., Xiao, Jianbo, John, Oliver D., Zou, Liang, Zhao, Gang, Simal-Gandara, Jesus   +16 more
core   +1 more source

Myorelaxation, respiratory depression and electrocardiographic changes caused by the administration of extract of açai (Euterpe oleracea Mart.) stone in rats

Toxicology Reports, 2021
The biological and pharmacological properties of natural polyphenols of the extract of Euterpe oleracea stone (EEOS) are associated with the central nervous system (CNS).
Nilton Akio Muto, Moisés Hamoy, David Cristian Rodrigues Lucas, Bruno Brito Teixeira, Adrielle Felicia Santos Almeida, Thamires de Castro Navegantes, Vaniza Sheila de Sousa Ferreira de Sá, Brenda Pinto de Moraes, João Paulo do Vale Medeiros, Yasmin Amorim dos Santos, Claúdia Quintino da Rocha, Vanessa Joia de Mello, Hervé Rogez   +12 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Streptomyces-Derived Bioactive Pigments: Ecofriendly Source of Bioactive Compounds

, 2022
Pigments have been used since historical times and are currently used in food, cosmetic, pharmaceutical, and other industries. One of the main sources of natural pigments are plants and insects; however, microorganisms are of great interest due to their ...
Laura Silva, Luis Diaz, Jeysson Sánchez-Suárez, Aixa A. Sarmiento-Tovar   +3 more
core   +1 more source