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Bioactive technologies for hemocompatibility
Expert Review of Medical Devices, 2005The contact of any biomaterial with blood gives rise to multiple pathophysiologic defensive mechanisms such as activation of the coagulation cascade, platelet adhesion and activation of the complement system and leukocytes. The reduction of these events is of crucial importance for the successful clinical performance of a cardiovascular device.
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2017
Ionic liquids are well-known for their remarkable physical and chemical properties, which triggered their use as green-solvents and materials with unique and tuneable characteristics. This tuneability frequently relies on just selecting suitable ions for a specific need rather than on complex covalent modifications, making ionic liquids attractive for ...
Ferraz, Ricardo +3 more
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Ionic liquids are well-known for their remarkable physical and chemical properties, which triggered their use as green-solvents and materials with unique and tuneable characteristics. This tuneability frequently relies on just selecting suitable ions for a specific need rather than on complex covalent modifications, making ionic liquids attractive for ...
Ferraz, Ricardo +3 more
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Bioassays for Bioactivity Screening
2014Abstract Bioassays are essential for the discovery of novel bioactive compounds as lead structures mostly for medicinal purpose. The goal of a bioactivity-directed isolation process is to isolate bioactive compounds that are capable of curing or alleviating a human or animal ailment and can either be ultimately developed as established drugs directly
Sofia Isabel G.H.M. Montalvão +2 more
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