Results 61 to 70 of about 139,903 (289)
Advanced Science, EarlyView.The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang +9 more
wiley +1 more source
Identification of putative steroid receptor antagonists in bottled water : combining bioassays and high-resolution mass spectrometry [PDF]
, 2013 Endocrine disrupting chemicals (EDCs) are man-made compounds interfering with hormone signaling and thereby adversely affecting human health. Recent reports provide evidence for the presence of EDCs in commercially available bottled water, including ...
Oehlmann, Jörg +3 more
core +8 more sources
Standard culture of Paratanytarsus grimmii Schneider, 1885 (Diptera: Chironomidae), for its use in toxicity bioassays. [PDF]
Brazilian Journal of Biology, 2019 The management and use of native species under laboratory conditions is the main difficult for species proposal for its use in bioassays. The present study showed the results about management under controlled conditions of Paratanytarsus grimmii (Diptera:
F. Encina +3 more
doaj +1 more source
Codling moth granulovirus: Variations in the susceptibility of local codling moth populations [PDF]
, 2006 This study is part of a BMELV (German Federal Ministry for, Food, Agriculture and Consumer Protection) project for prevention of codling moth damage by long-term population control in large areas.
Fritsch, Eva +4 more
core
Advanced Science, EarlyView.PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia +14 more
wiley +1 more source
Valorization of Amazonian Fruit Biomass for Biosurfactant Production and Nutritional Applications
BiomassProcessing economically and socio-culturally significant Amazonian fruits—andiroba (Carapa guianensis Aubl.), açai (Euterpe oleracea Mart.), and babassu (Attalea speciosa Mart.
Alan Moura Feio +12 more
doaj +1 more source
Variation in physiological host range in three strains of two species of the entomopathogenic fungus Beauveria [PDF]
, 2018 Knowledge of the host range of a biocontrol agent (BCA) is fundamental. Host range determines the BCA's economic potential, as well as the possible risk for non-target organisms. Entomopathogenic fungal strains belonging to the genus Beauveria are widely
Besse, Samantha +8 more
core +2 more sources
Advanced Science, EarlyView.This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li +9 more
wiley +1 more source
AI‐Driven Acceleration of Fluorescence Probe Discovery
Advanced Science, EarlyView.We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang +18 more
wiley +1 more source