Results 101 to 110 of about 469,546 (342)

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

Spatial and temporal trends in total organic carbon (TOC), black carbon (BC), and total nitrogen (TN) and their relationships under different planting patterns in a restored coastal mangrove wetland: case study in Fujian, China

open access: yesChemical Speciation & Bioavailability, 2018
This study aims to determine the sediment changes and the trends in TOC, BC and TN before and after restoration of the mangrove wetland in the Jinjiang Estuary and to determine the effect of the wetland restoration process on the biogeochemical cycle of ...
Peiyong Guo   +4 more
doaj   +1 more source

Role of Marine Snows in Microplastic Fate and Bioavailability.

open access: yesEnvironmental Science and Technology, 2018
Microplastics contaminate global oceans and are accumulating in sediments at levels thought sufficient to leave a permanent layer in the fossil record.
A. Porter   +3 more
semanticscholar   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

open access: yesAdvanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun   +13 more
wiley   +1 more source

Effects of root exudates on the sorption of polycyclic aromatic hydrocarbons onto biochar

open access: yesEnvironmental Pollutants & Bioavailability, 2019
The effect of oxalic acid on phenanthrene sorption was varied from that on pyrene sorption. 1.0 mg L-1 of oxalic acid inhibited phenanthrene sorption, whereas 20, 50 and 100 mg L-1 of oxalic acid enhanced the sorption.
Xiaona Li   +6 more
doaj   +1 more source

Bioavailability to Rats of Zinc, Magnesium and Calcium in Casein-, Egg- and Soy Protein-Containing Diets [PDF]

open access: bronze, 1979
Richard Forbes   +4 more
openalex   +1 more source

Advanced Oral Delivery Systems for Nutraceuticals

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang   +4 more
wiley   +1 more source

Spatial distribution of total halogenated organic compounds (TX), adsorbable organic halogens (AOX), and heavy metals in wetland soil irrigated with pulp and paper wastewater

open access: yesChemical Speciation & Bioavailability, 2017
Long-term irrigation using wastewater from paper industry may cause seriously problems to the receiving soil. This work surveyed and monitored the soil quality of a wastewater irrigation wetland system in Yancheng City, Jiangsu Province in China in 2014 ...
Liqiang Cui   +8 more
doaj   +1 more source

Mechanobiologically Engineered Mimicry of Extracellular Vesicles for Improved Systemic Biodistribution and Anti‐Inflammatory Treatment Efficacy in Rheumatoid Arthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Triblock copolymer‐reinforced liposomal mimics of extracellular vesicles are engineered with tunable membrane elasticity. A semi‐elastic formulation (Tri‐ARTEX8:2) co‐encapsulating stem cell cytosolic extract and AntagomiR155 targets inflamed joints via the ELVIS effect, reprograms macrophages from M1 to M2, and markedly alleviates collagen‐induced ...
Dahwun Kim   +11 more
wiley   +1 more source

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