Results 101 to 110 of about 719,874 (416)

Differences in reactivation of tuberculosis induced from anti-tnf treatments are based on bioavailability in granulomatous tissue [PDF]

open access: yes, 2007
The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection.
Denise E Kirschner   +7 more
core   +3 more sources

Bioavailability of copper [PDF]

open access: yesThe American Journal of Clinical Nutrition, 1996
Copper intakes of infants and adults are often much lower than current recommendations. Copper status, however, appears adequate in most populations. This suggests that copper requirements may be lower than believed earlier, except those for premature infants, who have high requirements as a result of low prenatal stores.
openaire   +3 more sources

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Pharmacokinetics of single‐dose rivaroxaban under fed state in obese vs. non‐obese subjects: An open‐label controlled clinical trial (RIVOBESE‐PK)

open access: yesClinical and Translational Science
The evidence of rivaroxaban's pharmacokinetics in obese compared with non‐obese populations remains inconclusive. We aimed to compare the pharmacokinetic profile of rivaroxaban between obese and non‐obese populations under fed state. Participants who met
Majdoleen Alalawneh   +9 more
doaj   +1 more source

Stream order and connectivity affect phosphorus distribution in plain river network

open access: yesEnvironmental Pollutants & Bioavailability, 2020
The order and connectivity of streams influence phosphorus distribution extensively. In this work, the space-and-time variabilities of total phosphorus (TP), particulate phosphorus (PP), total dissolved phosphorus (TDP), dissolved reactive phosphorus ...
Huihua Lyu, Feng Zhou, Na Li
doaj   +1 more source

On modelling of bioavailability of drugs in terms of conservation laws [PDF]

open access: yesarXiv, 2013
In the text S.Piekarski, M.Rewekant,(arXiv:1208.3847)it has been mentioned that some information on bioavailability and bioequivalence of drugs can be obtained from simulations based on the conservation laws. Here we shortly discuss that possibility starting from the fundamental pharmacokinetic parameter called AUC (Area Under the Curve).
arxiv  

Bioavailability of metals species in water ecosystem [PDF]

open access: yes, 2012
Koncentrace volných kovových iontů je často jen malou částí celkové koncentrace kovu v prostředí. Přes tento malý obsah, je ve většině případů koncentrace volných kovových iontů klíčovým faktorem při určování biodostupnosti a toxicity pro organizmus ...
Tandler, Ágnes
core  

Flavones: Food Sources, Bioavailability, Metabolism, and Bioactivity.

open access: yesAdvances in Nutrition, 2017
Flavones are a class of flavonoids that are a subject of increasing interest because of their biological activities in vitro and in vivo. This article reviews the major sources of flavones and their concentrations in food and beverages, which vary widely
Gregory L Hostetler   +2 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Evaluating the invasive plant, Prosopis juliflora in the two initial growth stages as a potential candidate for heavy metal phytostabilization in metalliferous soil

open access: yesEnvironmental Pollutants & Bioavailability, 2019
Anthropogenic activities leads to increase in toxic metals in the environment. The toxicity of Cd, Cr and Pb to P. juliflora were tested in agar media; Seeds germinated in 25, 50 and 100 mg/L Pb; 5, 10 and 20 mg/ 10 L Cd; and 10 mg/L Cr were mostly ...
Kamal Usman   +2 more
doaj   +1 more source

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