Results 131 to 140 of about 766,095 (388)

Synergistic Combination of Tamoxifen–Tetraphenylethylene Co‐Assembled Micelles and Orlistat‐Induced Lipid Droplet Inhibition to Overcome Tamoxifen Resistance

open access: yesAdvanced Healthcare Materials, EarlyView.
Molecule 2, which contains a shorter oligoether chain, binds to tamoxifen via structural similarity forming micelles with a positive surface charge, thereby enhancing cellular uptake. These fluorescent micelles induce lipid droplet (LD) accumulation, exhibit strong fluorescence, and effectively overcome tamoxifen resistance by synergizing with orlistat‐
Jung Yeon Park   +4 more
wiley   +1 more source

Efficient adsorptive removal of Congo red from aqueous solution by synthesized zeolitic imidazolate framework-8

open access: yesChemical Speciation & Bioavailability, 2016
Dyes exposure in aquatic environment creates risks to human health and biota due to their intrinsic toxic mutagenic and carcinogenic characteristics.
Canlan Jiang   +3 more
doaj   +1 more source

Indoor and outdoor concentration of PM10, PM2.5 and PM1 in residential building and evaluation of negative air ions (NAIs) in indoor PM removal

open access: yesEnvironmental Pollutants & Bioavailability, 2020
The present work was conducted in a two-part study. In part I, the levels of indoor and outdoor PM10, PM2.5, and PM1 was measured using real time GRIMM dust monitors.
Azam Nadali   +3 more
doaj   +1 more source

Assessment of trace element pollution and its environmental risk to freshwater sediments influenced by anthropogenic contributions: The case study of Alqueva reservoir (Guadiana Basin) [PDF]

open access: yes, 2015
The Guadiana Basin.(SW Iberian Peninsula) is affected by acid mine drainage (AMD), a consequence of ancient mining activities in the Iberian Pyrite Belt (IPB).
Alvarenga, Paula   +2 more
core   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun   +9 more
wiley   +1 more source

Phenolic metabolites of anthocyanins modulate mechanisms of endothelial function [PDF]

open access: yes, 2015
Anthocyanins are reported to have vascular bioactivity, however their mechanisms of action are largely unknown. Evidence suggests that anthocyanins modulate endothelial function, potentially by increasing nitric oxide (NO) synthesis, or enhancing NO ...
Cassidy, Aedin   +4 more
core   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo   +3 more
wiley   +1 more source

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

open access: yesAdvanced Healthcare Materials, EarlyView.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng   +7 more
wiley   +1 more source

Chemical speciation and bioavailability of cadmium and lead in the gray calcium soil

open access: yesEnvironmental Pollutants & Bioavailability, 2019
A pot experiment was conducted to study chemical speciations and bioavailability of cadmium (Cd) and lead (Pb) in the gray calcium soil from northwestern China, and accumulation and translocation of Cd and Pb in wheat (Triticum aestivum L.) grown on the ...
Yiming Yang, Liang Zeng, Lihua Chen
doaj   +1 more source

Design and in Vitro Evaluation of a New Nano-Microparticulate System for Enhanced Aqueous-Phase Solubility of Curcumin [PDF]

open access: yes, 2013
Curcumin, a yellow polyphenol derived from the turmeric Curcuma longa, has been associated with a diverse therapeutic potential including anti-inflammatory, antioxidant, antiviral, and anticancer properties.
El-Sherbiny, Ibrahim M.   +3 more
core   +2 more sources

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