Results 171 to 180 of about 469,546 (342)

Estimation of the Relative Bioavailability of Manganese Sources for Sheep2 [PDF]

, 1989
JOSE WONG-VALLE, P. R. Henry, C. B. Ammerman, P. V. Rao   +3 more
openalex   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Effect of Quantitative Structural Properties and Drug Formulation in Four Cannabinoids (Cannabidiol, Cannabigerol, Cannabichromene, and Cannabinol) on Their Lymphatic Transport after Enteral Administration in Rats. [PDF]

Mol Pharm
Ryšánek P, Jelínek P, Housar H, Kozlík P, Křížek T, Nováková A, Sklenárová M, Paulusová V, Merdita S, Arora M, Symkanych O, Šteigerová M, Zmeškalová E, Slanař O, Šoóš M, Šíma M.   +15 more
europepmc   +1 more source

Effect of food on the bioavailability of labetalol. [PDF]

, 1980
R Mäntylä, Hannu Allonen, J Kanto, T Kleimola, R. Sellman   +4 more
openalex   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Correction: Pharmacokinetic evaluation and bioavailability of KPT-335 (Verdinexor) in cats. [PDF]

Front Vet Sci
Frontiers Production Office.
europepmc   +1 more source

Particle size distribution affects the human bioavailability of phenytoin.

, 1986
SHIGERU YAKOU, Sachiko Yamazaki, Takashi Sonobe, MASAYASU SUGIHARA, Kenji Fukumuro, Tsuneji Nagai   +5 more
openalex   +2 more sources

Chemical Characterization and Bioavailability of Phosphorus in Water-Insoluble Fractions of Three Mono-Ammonium Phosphate Fertilizers [PDF]

, 1989
F. J. Sikora, E. F. Dillard, J. P. Copeland, Gray Mullins   +3 more
openalex   +1 more source

Carrier‐Free Nanocapsule with Dual‐Target Capacity for Synergistically Restoring Inflammatory Microenvironment and Microbiota Dysbiosis in Colitis

Advanced Science, EarlyView.
This manuscript presents a carrier‐free nanomedicine PCNPs@PEG‐Man with dual‐targeting for IBD. It resists harsh intestinal conditions, reduces oxidative stress, enhances drug uptake and retention, modulates inflammation, and reshapes gut microbiota, offering a safe and effective IBD therapy.
Yingjie Chen, Yuhan Gao, Kaiyuan Huo, Zhaofan Jin, Wenchao Wang, Xingjie Zan, Yanlong Liu, Limeng Zhu, Jianfeng Yang   +8 more
wiley   +1 more source

Recent advancement of fisetin-based nanoformulations in the management of psoriasis. [PDF]

Discov Nano
Telrandhe UB, Hasnain AN, Kothawade SN, Telange DR.   +3 more
europepmc   +1 more source