Results 91 to 100 of about 991,955 (291)

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

Ai-Fen Solid Dispersions: Preparation, Characterization, and Enhanced Therapeutic Efficacy in a Rat Model of Oral Ulceration

open access: yesPharmaceuticals
Background/Objectives: Recurrent oral ulceration (ROU) is the most prevalent disorder of the oral mucosa, affecting approximately 20% of the global population. Current therapies are limited by adverse effects and high recurrence rates.
Bing-Nan Liu   +10 more
doaj   +1 more source

Bioavailability of nutrients for animals : amino acids, minerals, and vitamins /

open access: yes, 1995
This practical book provides crucial information necessary to formulate diets with appropriate amounts of amino acids, minerals, and vitamins. The factors that influence how well animals obtain these critical nutrients and methods for determining ...
Baker, David H.(David Hiram),1939-2009.   +2 more
core  

Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system [PDF]

open access: yes, 2010
The self-microemulsifying drug delivery system (SMEDDS) was employed to improve the bioavailability of sulpiride, a drug which is poorly soluble. The mean droplet size and emulsification time of the test formulation used for in vivo study were 9.27 ± 2.
Janagama, Srujana   +3 more
core  

MICROENCAPSULATION BY SOLVENT EVAPORATION METHOD OF BCS CLASS 4 DRUGS FOR BIOAVAILABILITY ENHANCEMENT [PDF]

open access: yes, 2016
The microencapsulation process is used for size reduction with enclosing polymer coat on active pharmaceutical ingredient. The microencapsulation process used in present study is solvent evaporation process which formulated prior as o/o emulsification ...
Biyani, Kailash R, Pande, Swapnil V
core   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang   +6 more
wiley   +1 more source

Breaking the Solubility-Permeability Tradeoff: Surfactant-Mediated Enhancement of Oral Etoposide Absorption

open access: yesBiomolecules
Developing effective oral formulations for poorly soluble anticancer drugs remains a major pharmaceutical challenge due to the combined limitations of solubility, permeability, and efflux transporter activity.
Noa Fine-Shamir, Avital Beig, Arik Dahan
doaj   +1 more source

Nanostructured lipid carriers: A platform to lipophilic drug for oral bioavailability enhancement [PDF]

open access: yes, 2019
Lipid based drug delivery system such as Solid lipid nanoparticle (SLN) and Nanostructured lipid carriers (NLC) are among the most promising drug delivery system used in many industries such as food, pharmaceuticals and cosmetics industries.
Patil, Deepak   +4 more
core   +1 more source

https://www.healthlinepalace.com/health-flow-male-enhancement

open access: yes, 2021
Health Flow Male Enhancement This is mainly because synthetic herbal enhancement Mega XL Advantage products are chemically based and they directly target the area of the body system where it needs reconditioning.
Health Flow Male Enhancement
core   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

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