Results 91 to 100 of about 54,975 (247)

An Overview of Nanoemulgels for Bioavailability Enhancement in Inflammatory Conditions via Topical Delivery. [PDF]

Pharmaceutics, 2023
Lal DK, Kumar B, Kumar B, Saeedan AS, Ansari MN.   +4 more
europepmc   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Strategies for Solubility and Bioavailability Enhancement and Toxicity Reduction of Norcantharidin. [PDF]

Molecules, 2022
Liu Q, Sun H, Li X, Sheng H, Zhu L.
europepmc   +1 more source

Oligopeptides/DNA Coacervate Droplets as Macromolecular Delivery Microcarriers

Advanced Science, EarlyView.
Oligopeptide–DNA coacervates formed via liquid–liquid phase separation serve as programmable carriers for macromolecular cargos, entering cells through lipid raft–associated pathways and subsequently undergoing enzyme triggered intracellular disassembly driven by DNA degradation processes, thereby enabling efficient, controlled, and spatially defined ...
Linyi Zhang, Chong Wang, Mengqi Han, Yi Yang, Teng Ma, Luoran Shang   +5 more
wiley   +1 more source

Mechanistic approach for the development of ultrafine o/w emulsions using blends medium and long chain triglycerides: solubility and bioavailability enhancement of perphenazine

, 2013
A thermodynamically stable ultrafine (o/w) emulsion containing perphenazine for solubility and oral bioavailability enhancement using blends of long and medium chain triglyceride was developed.
Ali, Javed, Baboota, Sanjula, Sahni, Jasjeet Kaur, Abdullah, Abdullah, Mustafa, Gulam   +4 more
core  

STUDIES ON BIOAVAILABILITY ENHANCEMENT OF CURCUMIN

, 2020
Objective: The objective of the present work was to improve aqueous solubility and in vivo bioavailability of curcumin and structural analogues of curcumin such as potassium, calcium, magnesium salts and nitro derivative. Methods: Structural analogues of
KOTAGALE, N. R., CHARDE, P. B., UMEKAR, M. J., RAUT, N. S., HELONDE, A., GUPTA, K. R.   +5 more
core   +1 more source

Enhancing Osteoporosis Treatment through Targeted Nanoparticle Delivery of Risedronate: In Vivo Evaluation and Bioavailability Enhancement. [PDF]

Pharmaceutics, 2023
Saifi Z, Shafi S, Ralli T, Jain S, Vohora D, Mir SR, Alhalmi A, Noman OM, Alahdab A, Amin S.   +9 more
europepmc   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

Advanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang, Guoruiyu Lyu, Wenlong Wan, Dongfeng Yuan, Jiabo Li, Yongqi Wang, Baokang Wang, Zhilong Ma, Yuanyuan Yang, Yang Xun, Xiao Yu   +10 more
wiley   +1 more source

Application of Sucrose Acetate Isobutyrate in Development of Co-Amorphous Formulations of Tacrolimus for Bioavailability Enhancement. [PDF]

Pharmaceutics, 2023
Mohamed EM, Dharani S, Nutan MTH, Cook P, Arunagiri R, Khan MA, Rahman Z.   +6 more
europepmc   +1 more source