Results 81 to 90 of about 991,955 (291)

Oral bioavailability enhancement of agomelatine by loading into nanostructured lipid carriers: Peyer’s patch targeting approach

, 2018
Jagruti B Prajapati, Sneha D Verma, Amit A Patel Department of Ppharmaceutics and Ppharmaceutical Technology, Rramanbhai Patel College of Ppharmacy, Charotar University of Science and Technology, Changa, Gujarat, India Abstract: Agomelatine (AGM) is a ...
Prajapati JB, Verma SD, Patel AA
core  

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

The Carbon Dots from Seabuckthorn (Hippophae rhamnoides L.) Leaves: Recycle the Herbal Waste Products for a Nano-Formulation in Delivering Bioactive Compounds

Journal of Functional Biomaterials
Carbon dots have emerged as promising nanocarriers for drug delivery due to their unique physicochemical properties and biocompatibilities. Here, the potential of leaf-derived carbon dots (named as SBLCD), derived from Seabuckthorn (Hippophae rhamnoides ...
Chen-Xi Xia, Xiong Gao, Queenie Wing-Sze Lai, Zheng-Qi Wang, Lish Sheng-Yin Lin, Janet Yuen-Man Ho, Jia-Yu Zhu, Roy Wai-Lun Tang, Tina Ting-Xia Dong, Karl Wah-Keung Tsim   +9 more
doaj   +1 more source

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

Advanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz, A. Bandyopadhyay, S. Belkin, S. Bose, N. Eliaz, J. L. Gilbert, T. C. Lowe, F. Mücklich, R. J. Turner, C. C. Tasan   +9 more
wiley   +1 more source

Development of transfersomal buccal patches of galantamine for enhanced bioavailability in Alzheimer’s disease therapy

Journal of Applied Pharmaceutical Research
Background: Galantamine, an acetylcholinesterase inhibitor used in Alzheimer’s disease, exhibits low and variable bioavailability due to gastrointestinal metabolism and first-pass hepatic elimination. Buccal drug delivery offers a non-invasive route that
Pavuluri Chandrasekhar, Rajaganapathy Kaliyaperumal   +1 more
doaj   +1 more source

Fishworks shop

, 2006
Covers OCLC #38937785, OCLC #1100114907"News from Oregon's Fish Restoration and Enhancement Program and Salmon Trout Enhancement Program."Title from captionErrors in numbering: v. 3, no. 1, spring 1998, called v. 2, no. 1; v. 3, no.

core  

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Antioxidant Delivery Revisited: The Promise of Nanostructured Lipid Carriers

Medicines
Natural products have an invaluable therapeutic effect on human health. Natural antioxidants, including beta-carotene, turmeric, and polyphenols, are recognised for their health benefits but face significant barriers related to insufficient solubility ...
Leif Behar, Holly Siddique
doaj   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

Berberine as a Multifunctional Adjuvant in Cancer Therapy: Mechanistic Insights, Nanotechnological Strategies, and Translational Challenges

Pharmaceuticals
Multidrug resistance (MDR) and chemotherapy-associated toxicity remain major challenges limiting the success of cancer treatments. In this context, berberine (BBR), an isoquinoline derivative belonging to the barberry family, has emerged as a promising ...
Yıldız Özalp, Tarek Alloush, Nedime Serakıncı, Murat Kartal   +3 more
doaj   +1 more source