Results 11 to 20 of about 171,678 (355)

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age [PDF]

PLoS Medicine, 2015
Cathie Sudlow and colleagues describe the UK Biobank, a large population-based prospective study, established to allow investigation of the genetic and non-genetic determinants of the diseases of middle and old age.
C. Sudlow, J. Gallacher, N. Allen, V. Beral, P. Burton, J. Danesh, P. Downey, P. Elliott, J. Green, M. Landray, Bette Liu, P. Matthews, G. Ong, J. Pell, A. Silman, A. Young, Tim Sprosen, T. Peakman, R. Collins   +18 more
semanticscholar   +2 more sources

Biobank linked to SWEDEHEART quality registry—routine blood sample collection opens new opportunities for cardiovascular research

Upsala Journal of Medical Sciences, 2019
High-quality biobanking within routine health services, through the use of existing health-care practices and infrastructure, with respect to safety and integrity of patients in line with the Swedish Biobank Act, enables large-scale collection of ...
Tomasz Baron, Anna Beskow, Stefan James, Bertil Lindahl   +3 more
doaj   +2 more sources

Health Outcomes Linkage in UK Biobank [PDF]

International Journal of Population Data Science
UK Biobank is a biomedical database containing de-identified data for over 500,000 participants within the United Kingdom, made globally available to researchers for health-related research in the public interest.
Laura Bramley, Jo Gay, Christopher de Lacy, Howard Callen, Sean Rose, Amy Flaxman, Gemma Codner, Rachael Drake-Brockman, Ben Lacey, Naomi Allen   +9 more
doaj   +2 more sources

Cohort profile:rationale and methods of UK Biobank repeat imaging study eye measures to study dementia [PDF]

, 2023
PURPOSE: The retina provides biomarkers of neuronal and vascular health that offer promising insights into cognitive ageing, mild cognitive impairment and dementia.
Anthony Khawaja, Allen, Naomi, Atan, Denize, Foster, Paul, Denize Atan, Rudnicka, Alicja, Khawaja, Anthony, Lotery, Andrew, Patel, Praveen J., Praveen J Patel, MacGillivray, Tom; id_orcid, Andrew Lotery, Khawaja, Anthony P., Foster, Paul J, Owen, Christopher G., Petzold, Axel, Zihan Sun, Simon Sheard, Alicja Rudnicka, Sun, Zihan, Sheard, Simon, Owen, Christopher G, ?, ?, Paul J Foster, Patel, Praveen J, Rudnicka, Alicja R., Tom MacGillivray, MacGillivray, Tom, Naomi Allen, Christopher G Owen, Axel Petzold   +30 more
core   +5 more sources

Pathology and biobanking [PDF]

Turkish Journal of Pathology, 2020
Biobanks are units where high quality and long-term protection of biomaterials is maintained. This system, in which biological materials and data are systematically recorded and stored, is a unique resource for the study of the pathophysiology of disease, the development of diagnostic biomarkers, and working with human tissues for the potential ...
Kelten Talu, Canan, Erdogdu, Ibrahim Halil, Sahin, Yasemin, Toper, Muhammed Hasan   +3 more
openaire   +4 more sources

Plasma proteomic associations with genetics and health in the UK Biobank

Nature, 2023
The Pharma Proteomics Project generates the largest open-access plasma proteomics dataset to date, offering insights into trans protein quantitative trait loci across multiple biological domains, and highlighting genetic influences on ligand–receptor ...
B. Sun, Joshua Chiou, M. Traylor, C. Benner, Yi-Hsiang Hsu, T. G. Richardson, P. Surendran, A. Mahajan, Chloe Robins, Steven G. Vasquez-Grinnell, Liping Hou, E. Kvikstad, O. Burren, J. Davitte, Kyle L. Ferber, C. Gillies, Åsa K. Hedman, Sile Hu, Tinchi Lin, Rajesh Mikkilineni, R. Pendergrass, Corran Pickering, Bram Prins, D. Baird, Chia-Yen Chen, Lucas D. Ward, A. Deaton, Samantha Welsh, Carissa M. Willis, Nick Lehner, M. Arnold, Maria A. Wörheide, Karsten Suhre, G. Kastenmüller, A. Sethi, M. Cule, Anil Raj, H. Kang, L. Burkitt-Gray, E. Melamud, Mary Helen Black, E. Fauman, J. Howson, H. M. Kang, M. McCarthy, P. Nioi, S. Petrovski, Robert A. Scott, E. Smith, S. Szalma, D. Waterworth, L. Mitnaul, J. Szustakowski, Brad Gibson, Melissa R. Miller, Christopher D. Whelan   +55 more
semanticscholar   +1 more source

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

Nature, 2022
There is strong evidence of brain-related abnormalities in COVID-191–13. However, it remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain ...
G. Douaud, Soojin Lee, F. Alfaro-Almagro, C. Arthofer, Chaoyue Wang, P. McCarthy, F. Lange, Jesper L. R. Andersson, L. Griffanti, E. Duff, S. Jbabdi, B. Taschler, P. Keating, A. Winkler, Rory Collins, P. Matthews, Naomi Allen, K. Miller, Thomas E. Nichols, Stephen M. Smith   +19 more
semanticscholar   +1 more source

Polymorphism of E6 and E7 Genes in Human Papillomavirus Types 31 and 33 in Northeast China

Canadian Journal of Infectious Diseases and Medical Microbiology, 2023
Persistent infection with human papillomavirus (HPV) types 31 and 33 is an important causative factor for cervical cancer. The E6/E7 genes are key oncogenes involved in the immortalization and transformation of human epithelial cells.
Miao Yu, Si Wu, Shuang Wang, Changwan Cui, Yiping Lu, Zhengrong Sun   +5 more
doaj   +1 more source

National Center Biobank Network

Human Genome Variation, 2022
Biobanks: Japanese network promotes research collaboration Japan’s National Center Biobank Network (NCBN) has standardized the collection and storage of high-quality disease-related data and samples, offering collaboration opportunities in basic and ...
Yosuke Omae, Yu-ichi Goto, Katsushi Tokunaga   +2 more
doaj   +1 more source

Biobanks for genomics and genomics for biobanks [PDF]

Comparative and Functional Genomics, 2003
AbstractBiobanks include biological samples and attached databases. Human biobanks occur in research, technological development and medical activities. Population genomics is highly dependent on the availability of large biobanks. Ethical issues must be considered: protecting the rights of those people whose samples or data are in biobanks (information,
Cambon-Thomsen, Anne, Ducournau, Pascal, Gourraud, P.A., Pontille, David   +3 more
openaire   +5 more sources