Results 41 to 50 of about 171,678 (355)

DescribePSP and ProPSP: German Multicenter Networks for Standardized Prospective Collection of Clinical Data, Imaging Data, and Biomaterials of Patients With Progressive Supranuclear Palsy

Frontiers in Neurology, 2021
Background: The German research networks DescribePSP and ProPSP prospectively collect comprehensive clinical data, imaging data and biomaterials of patients with a clinical diagnosis of progressive supranuclear palsy.
Gesine Respondek, Günter U. Höglinger, Günter U. Höglinger, Günter U. Höglinger   +3 more
doaj   +1 more source

Commercialization of Biobanks [PDF]

Biopreservation and Biobanking, 2012
Biobank policy and regulations profoundly vary between different societies. One area with profound differences in culture and tradition concerns commercialization, and the possibility of using the human body as a capital resource. In the United States there is acceptance of this possibility, whereas European law is based on principles that ...
Evers, Kathinka; Forsberg, Joanna; Hansson, Mats   +3 more
openaire   +2 more sources

Sustained agreement rates in the longitudinal assessment of lupus patients to a Broad Consent for personal data and specimen usage in the RHINEVIT biobank

Frontiers in Medicine, 2023
BackgroundBiobanks are essential structures for scientific research. The RHINEVIT biobank is used to recruit biomaterials from rheumatology patients in outpatient care and to conduct clinical research studies (e.g., cohort studies) and basic research ...
Jutta G. Richter, Jutta G. Richter, Tim Filla, Tim Filla, Hasan Acar, Hasan Acar, Ellen Bleck, Ellen Bleck, Anna Kernder, Anna Kernder, Christina Düsing, Christina Düsing, Stefan Vordenbäumen, Stefan Vordenbäumen, Markus Schröder, Ralf Hansen, Jörg H. W. Distler, Jörg H. W. Distler, Matthias Schneider, Matthias Schneider   +19 more
doaj   +1 more source

amazon-biobank/biobank: v0.1.1

, 2022
A prototype for a community-based genetic database using ...
leonardotkimura, Vinícius
core   +1 more source

Systemic inflammation markers and cancer incidence in the UK Biobank

European Journal of Epidemiology, 2021
Systemic inflammation markers have been linked to increased cancer risk and mortality in a number of studies. However, few studies have estimated pre-diagnostic associations of systemic inflammation markers and cancer risk.
T. Nøst, K. Alcala, I. Urbarova, K. Byrne, F. Guida, T. Sandanger, M. Johansson   +6 more
semanticscholar   +1 more source

PRSice-2: Polygenic Risk Score software for biobank-scale data

GigaScience, 2019
Background Polygenic risk score (PRS) analyses have become an integral part of biomedical research, exploited to gain insights into shared aetiology among traits, to control for genomic profile in experimental studies, and to strengthen causal inference,
S. Choi, P. O’Reilly
semanticscholar   +1 more source

Rare variant associations with plasma protein levels in the UK Biobank

Nature, 2023
Integrating human genomics and proteomics can help elucidate disease mechanisms, identify clinical biomarkers and discover drug targets^ 1 – 4 . Because previous proteogenomic studies have focused on common variation via genome-wide association studies ...
R. Dhindsa, O. Burren, B. Sun, Bram Prins, D. Matelska, Eleanor Wheeler, J. Mitchell, E. Oerton, V. Hristova, Katherine R Smith, K. Carss, S. Wasilewski, A. Harper, Dirk S. Paul, M. Fabre, H. Runz, Coralie Viollet, B. Challis, A. Platt, Rasmus Lauren Santosh David Carl Maria Mohammad Lisa Nied Ågren Anderson-Dring Atanur Baker Barrett Belvisi , Rasmus Ågren, Lauren Anderson-Dring, S. Atanur, David Baker, Carl Barrett, Maria G. Belvisi, Mohammad Bohlooly-Y, Lisa Buvall, Niedzica Camacho, L. Cazares, Sophia Cameron-Christie, Mo-shui Chen, Suzanne Cohen, R. F. Danielson, Shikta Das, Andrew Davis, S. V. Deevi, Wei Ding, B. Dougherty, Z. Fairhurst-Hunter, M. Garg, B. Georgi, Carmen Guerrero Rangel, C. Haefliger, M. Hammar, Richard N. Hanna, Pernille B. L. Hansen, J. Harrow, I. Henry, S. Hess, Ben Hollis, Fengyuan Hu, Xiao Jiang, Kousik Kundu, Z. Lai, Mark Lal, G. Lassi, Yupu Liang, Margarida Lopes, Kieren T. Lythgow, S. MacArthur, Meeta Maisuria-Armer, Ruth E. March, Carla Martins, Karine Megy, Rob Menzies, E. Michaëlsson, Fiona Middleton, B. Mowrey, D. Muthas, Abhishek Nag, Sean O’Dell, Y. Ohne, H. Olsson, A. O’Neill, K. Ostridge, B. Pullman, W. Rae, A. Raies, A. Reznichenko, X. R. Ros, Maria Ryaboshapkina, Hitesh Sanganee, Ben S Sidders, Mike Snowden, Stasa Stankovic, H. Stevens, I. Tachmazidou, Haeyam Taiy, Lifeng Tian, C. Underwood, A. Walentinsson, Qing-Dong Wang, A. Zehir, Zoe Zou, D. Vitsios, Euan A. Ashley, Christopher D. Whelan, M. Pangalos, Quanli Wang, S. Petrovski   +100 more
semanticscholar   +1 more source

Clinical biomarker-based biological aging and risk of cancer in the UK Biobank

British Journal of Cancer, 2023
Despite a clear link between aging and cancer, there has been inconclusive evidence on how biological age (BA) may be associated with cancer incidence. We studied 308,156 UK Biobank participants with no history of cancer at enrolment.
Jonathan K. L. Mak, C. McMurran, R. Kuja-Halkola, P. Hall, K. Czene, J. Jylhävä, S. Hägg   +6 more
semanticscholar   +1 more source

Risk Factors for Young-Onset Dementia in the UK Biobank.

JAMA Neurology, 2023
Importance There is limited information on modifiable risk factors for young-onset dementia (YOD). Objective To examine factors that are associated with the incidence of YOD.
Stevie Hendriks, J. Ranson, K. Peetoom, Ilianna Lourida, Xin You Tai, M. D. de Vugt, D. Llewellyn, S. Köhler   +7 more
semanticscholar   +1 more source

Complex Feline Disease Mapping Using a Dense Genotyping Array

Frontiers in Veterinary Science, 2022
The current feline genotyping array of 63 k single nucleotide polymorphisms has proven its utility for mapping within breeds, and its use has led to the identification of variants associated with Mendelian traits in purebred cats.
Isabel Hernandez, Jessica J. Hayward, Jeff A. Brockman, Michelle E. White, Michelle E. White, Lara Mouttham, Elizabeth A. Wilcox, Susan Garrison, Marta G. Castelhano, John P. Loftus, Filipe Espinheira Gomes, Cheryl Balkman, Marjory B. Brooks, Nadine Fiani, Marnin Forman, Tom Kern, Bruce Kornreich, Eric C. Ledbetter, Santiago Peralta, Angela M. Struble, Lisa Caligiuri, Elizabeth Corey, Lin Lin, Julie Jordan, Danny Sack, Adam R. Boyko, Leslie A. Lyons, Rory J. Todhunter   +27 more
doaj   +1 more source