Results 41 to 50 of about 147,982 (310)

Risk mapping for better governance in biobanking: the case of biobank.cy

Frontiers in Genetics
Introduction: Risk governance is central for the successful and ethical operation of biobanks and the continued social license for being custodians of samples and data. Risks in biobanking are often framed as risks for participants, whereas the biobank’s
Kaya Akyüz, Melanie Goisauf, Gillian M. Martin, Michaela Th. Mayrhofer, Stella Antoniou, Georgia Charalambidou, Constantinos Deltas, Constantinos Deltas, Apostolos Malatras, Gregory Papagregoriou, Charalambos Stefanou, Mariel Voutounou   +11 more
doaj   +1 more source

Access to Biobanks: Harmonization Across Biobank Initiatives [PDF]

Biopreservation and Biobanking, 2014
The current study investigates whether access arrangements relevant for biobanking contain clear information on key access conditions. It furthermore assesses the extent to which these access conditions are harmonized across biobank initiatives.A comparative analysis was conducted of access arrangements developed by 26 organizations, 36 biobank ...
Michiel, Verlinden, Herman, Nys, Nadine, Ectors, Isabelle, Huys   +3 more
openaire   +3 more sources

Commercialisation fears and preferred forms of governance: a mixed methods investigation to identify a trusted Australian genomics repository

Frontiers in Public Health
This study aimed to identify operating conditions and governance mechanisms that would help to facilitate trust in, and willingness to donate to, a hypothetical Australian national genomic repository for health research where commercial use of data is ...
Brad Elphinstone, Jarrod Walshe, Dianne Nicol, Mark Taylor   +3 more
doaj   +1 more source

Living biobank-based cancer organoids: prospects and challenges in cancer research

Cancer Biology & Medicine, 2022
Biobanks bridge the gap between basic and translational research. Traditional cancer biobanks typically contain normal and tumor tissues, and matched blood. However, biospecimens in traditional biobanks are usually nonrenewable.
Haixin Li, Hongkun Liu, Kexin Chen
doaj   +1 more source

Characterisation of liver fat in the UK Biobank cohort [PDF]

, 2017
Non-alcoholic fatty liver disease and the risk of progression to steatohepatitis, cirrhosis and hepatocellular carcinoma have been identified as major public health concerns. We have demonstrated the feasibility and potential value of measuring liver fat
Garratt, S., Neubauer, S, Matthews, P., Milanesi, M., Thomas, E.L., Gyngell, M, Kelly, M., Bell, J.D., Herlihy, A.H., Banerjee, R, Wilman, H.   +10 more
core   +1 more source

Inter- and Intra-Biobank Networks: Classification of Biobanks [PDF]

Pathobiology, 2010
<i>Background:</i> Many biobanks have struggled to deliver on the high expectations and claims made for them because of insufficient samples, inadequate infrastructure, cost of establishing and maintaining a large enough resource over the long term, and satisfying legal, ethics and governance requirements. Increasingly, networks have formed
Darren, Shickle, Marcus, Griffin, Karen, El-Arifi   +2 more
openaire   +2 more sources

Justice and the Pandemic City: How the Pandemic Has Revealed Social, Urban, and Data Injustices, and How a Narrative Approach Can Unlock Them

Frontiers in Sustainable Cities, 2022
The global COVID-19 pandemic has exacerbated infrastructural, societal, and resource inequalities along racial and socioeconomic lines. Many countries have struggled to provide adequate COVID testing and healthcare.
Natalie Marie Gulsrud, Henriette Steiner
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes. [PDF]

Adv Sci (Weinh)
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Hu W, Ling Y, Hu X, Chen W, Zhou R, Zhuang X, Jiang Y, Zhao J, Chen X, Luo J, Jin L, Zhang G.   +11 more
europepmc   +2 more sources

Validation of Self-reported Medical Condition in the Taiwan Biobank

Journal of Epidemiology
Background: This study aimed to validate self-reported medical conditions in the Taiwan Biobank (TWBB), in which participants were inquired about 30 disease conditions, by comparing them with claims records from Taiwan’s National Health Insurance (NHI ...
Chi-Shin Wu, Le-Yin Hsu, Chen-Yang Shen, Wei J. Chen, Shi-Heng Wang   +4 more
doaj   +1 more source