Results 31 to 40 of about 191,359 (300)

Complex Feline Disease Mapping Using a Dense Genotyping Array

Frontiers in Veterinary Science, 2022
The current feline genotyping array of 63 k single nucleotide polymorphisms has proven its utility for mapping within breeds, and its use has led to the identification of variants associated with Mendelian traits in purebred cats.
Isabel Hernandez, Jessica J. Hayward, Jeff A. Brockman, Michelle E. White, Michelle E. White, Lara Mouttham, Elizabeth A. Wilcox, Susan Garrison, Marta G. Castelhano, John P. Loftus, Filipe Espinheira Gomes, Cheryl Balkman, Marjory B. Brooks, Nadine Fiani, Marnin Forman, Tom Kern, Bruce Kornreich, Eric C. Ledbetter, Santiago Peralta, Angela M. Struble, Lisa Caligiuri, Elizabeth Corey, Lin Lin, Julie Jordan, Danny Sack, Adam R. Boyko, Leslie A. Lyons, Rory J. Todhunter   +27 more
doaj   +1 more source

Cancer bio-repository [PDF]

Iranian Journal of Colorectal Research, 2019
Background: Cancer research is highly dependent of large amount of data and high quality samples which can be provided by networks to enable large-scale multi-center research projects.
Shima Fakher, Seyed Vahid Hosseini, Mozhdeh Zamani, Leila Ghahramani, Pooneh mokaram Mokaram   +4 more
doaj   +1 more source

Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies [PDF]

, 2017
We would like to thank all patients whose samples were used in this study. We are also thankful to the Northern Ireland Biobank and Grampian Biorepository for providing us with tissue blocks and patient data; and Dr HG Coleman (Queen’s University Belfast)
A Gonçalves, Brendan Pang, Claire McGready, CM McCourt, D Barras, DT Le, E Vilar, Graeme I Murray, J Guinney, J Siehl, Jacqueline A James, K Masago, KJ Lastwika, M Arnold, M Lek, M Toyota, MA Alvi, Manuel Salto-Tellez, Marc-Aurel Fuchs, Mark Lawler, Maurice B Loughrey, MF Kane, ML Iacono, Muhammad A Alvi, NJ Llosa, Perry Maxwell, Philip Dunne, Richard H Wilson, Richard Turkington, RS Herbst, S Kakar, SC Casey, Stephen McQuaid, T Anthony, The Genomes Project C, U Nitsche, V Gopalan, Victoria Bingham, Wendy Moore, Y Xiao   +39 more
core   +2 more sources

Living biobank-based cancer organoids: prospects and challenges in cancer research

Cancer Biology & Medicine, 2022
Biobanks bridge the gap between basic and translational research. Traditional cancer biobanks typically contain normal and tumor tissues, and matched blood. However, biospecimens in traditional biobanks are usually nonrenewable.
Haixin Li, Hongkun Liu, Kexin Chen
doaj   +1 more source

Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study [PDF]

, 2017
OBJECTIVE Grip strength and diabetes are predictors of mortality and cardiovascular disease (CVD), but whether these risk factors interact to predispose to adverse health outcomes is unknown.
Anderson, Jana, Celis-Morales, Carlos A., Gill, Jason M.R., Gray, Stuart R., Hui, Li, Iliodromiti, Stamatina, Lyall, Donald M., Mackay, Daniel F., McLaren, James, Pell, Jill P., Petermann, Fanny, Sattar, Naveed, Welsh, Paul   +12 more
core   +1 more source

Risk mapping for better governance in biobanking: the case of biobank.cy

Frontiers in Genetics
Introduction: Risk governance is central for the successful and ethical operation of biobanks and the continued social license for being custodians of samples and data. Risks in biobanking are often framed as risks for participants, whereas the biobank’s
Kaya Akyüz, Melanie Goisauf, Gillian M. Martin, Michaela Th. Mayrhofer, Stella Antoniou, Georgia Charalambidou, Constantinos Deltas, Constantinos Deltas, Apostolos Malatras, Gregory Papagregoriou, Charalambos Stefanou, Mariel Voutounou   +11 more
doaj   +1 more source

Justice and the Pandemic City: How the Pandemic Has Revealed Social, Urban, and Data Injustices, and How a Narrative Approach Can Unlock Them

Frontiers in Sustainable Cities, 2022
The global COVID-19 pandemic has exacerbated infrastructural, societal, and resource inequalities along racial and socioeconomic lines. Many countries have struggled to provide adequate COVID testing and healthcare.
Natalie Marie Gulsrud, Henriette Steiner
doaj   +1 more source

Ethnic specific obesity cut-offs for diabetes risk: cross-sectional study of 490, 288 UK Biobank participants [PDF]

, 2014
OBJECTIVE To compare the relationship between adiposity and prevalent diabetes across ethnic groups in the UK Biobank cohort and to derive ethnic-specific obesity cutoffs that equate to those developed in white populations in terms of diabetes prevalence.
Gill, Jason, Mackay, Daniel, Ntuk, Uduakobong, Pell, Jill, Sattar, Naveed   +4 more
core   +1 more source

Commercialisation fears and preferred forms of governance: a mixed methods investigation to identify a trusted Australian genomics repository

Frontiers in Public Health
This study aimed to identify operating conditions and governance mechanisms that would help to facilitate trust in, and willingness to donate to, a hypothetical Australian national genomic repository for health research where commercial use of data is ...
Brad Elphinstone, Jarrod Walshe, Dianne Nicol, Mark Taylor   +3 more
doaj   +1 more source

Investigating the need for antibiotic supplementation to the extender used for semen cryopreservation in collared peccaries

Frontiers in Veterinary Science, 2022
The objective was to investigate the effects of semen freezing extender supplementation with antibiotics on bacterial load of semen samples, sperm functional and morphological metrics in the collared peccary.
Samara S. J. Moreira, Caio S. Santos, Thibério S. Castelo, Luana G. P. Bezerra, Érica C. G. Praxedes, Tayná M. Matos, João B. F. Souza-Junior, Francisco M. C. Feijó, Pierre Comizzoli, Alexandre R. Silva   +9 more
doaj   +1 more source