Results 31 to 40 of about 171,678 (355)
Harmonization of Biobank Education for Biobank Technicians: Identification of Learning Objectives
, 2022 The quality of biospecimens stored in a biobank depends tremendously on the technical personnel responsible for processing, storage, and release of biospecimens.
Winter, Theresa; Integrated Research Biobank, University Medicine Greifswald, 17475 Greifswald, Germany, theresa.winter@med.uni-greifswald.de +15 more
core +1 more source
Exome sequencing and analysis of 454,787 UK Biobank participants
Nature, 2021 A major goal in human genetics is to use natural variation to understand the phenotypic consequences of altering each protein-coding gene in the genome. Here we used exome sequencing1 to explore protein-altering variants and their consequences in 454,787
J. Backman +40 more
semanticscholar +1 more source
Genetics of 35 blood and urine biomarkers in the UK Biobank
Nature Genetics, 2021 Clinical laboratory tests are a critical component of the continuum of care. We evaluate the genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n = 363,228 individuals).
Nicholas A. Sinnott-Armstrong +19 more
semanticscholar +1 more source
The UK Biobank resource with deep phenotyping and genomic data
Nature, 2018 The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data collected on approximately 500,000 individuals from across the United Kingdom, aged between 40 and 69 at recruitment.
Clare Bycroft +18 more
semanticscholar +1 more source
An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank
Nature Neuroscience, 2021 UK Biobank is a major prospective epidemiological study, including multimodal brain imaging, genetics and ongoing health outcomes. Previously, we published genome-wide associations of 3,144 brain imaging-derived phenotypes, with a discovery sample of 8 ...
Stephen M. Smith +6 more
semanticscholar +1 more source
Rare variant contribution to human disease in 281,104 UK Biobank exomes
Nature, 2021 Genome-wide association studies have uncovered thousands of common variants associated with human disease, but the contribution of rare variants to common disease remains relatively unexplored.
Quanli Wang +59 more
semanticscholar +1 more source
amazon-biobank/biobank: Demonstration
, 2022 Executable build for demonstration. Contains a testing credential for use by external users. Updates: reduced the number of channels from 2 to
leonardotkimura +3 more
core +1 more source
Biobank Łódź® – population based biobank at the University of Łódź, Poland [PDF]
, 2019 Biobank Laboratory of the University of Łódź is a unit in the organizational structure of the De- partment of Molecular Biophysics at the Faculty of Biology and Environmental Protection. It was established in 2014 as one of the results of the TESTOPLEK
Dobrowolska, Sylwia +4 more
core +1 more source
A generalized linear mixed model association tool for biobank-scale data
Nature Genetics, 2021 Compared with linear mixed model-based genome-wide association (GWA) methods, generalized linear mixed model (GLMM)-based methods have better statistical properties when applied to binary traits but are computationally much slower.
Longda Jiang +3 more
semanticscholar +1 more source
Cell Genomics, 2022 Summary Genome-wide association studies have successfully discovered thousands of common variants associated with human diseases and traits, but the landscape of rare variations in human disease has not been explored at scale. Exome-sequencing studies of
K. Karczewski +50 more
semanticscholar +1 more source