Results 21 to 30 of about 220,549 (336)

Alzheimer disease genetic risk factor APOE e4, and cognitive abilities in 111,739 UK Biobank participants [PDF]

, 2016
Background: the apolipoprotein (APOE) e4 locus is a genetic risk factor for dementia. Carriers of the e4 allele may be more vulnerable to conditions that are independent risk factors for cognitive decline, such as cardiometabolic diseases.
Anderson, Jana, Bailey, Mark E.S., Celis, Carlos, Cullen, Breda, Davies, Gail, Deary, Ian J., Evans, Jon, Lyall, Donald M., Mackay, Daniel, McIntosh, Andrew M., Pell, Jill P., Ritchie, Stuart J., Sattar, Naveed, Smith, Daniel J., Ward, Joey   +14 more
core   +1 more source

The UK Biobank resource with deep phenotyping and genomic data

Nature, 2018
The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data collected on approximately 500,000 individuals from across the United Kingdom, aged between 40 and 69 at recruitment.
Clare Bycroft, C. Freeman, D. Petkova, G. Band, L. Elliott, Kevin Sharp, A. Motyer, Damjan Vukcevic, Olivier Delaneau, Jared O'Connell, A. Cortes, S. Welsh, Alan Young, Mark Effingham, G. McVean, S. Leslie, N. Allen, P. Donnelly, J. Marchini   +18 more
semanticscholar   +1 more source

The European IPF registry (eurIPFreg): baseline characteristics and survival of patients with idiopathic pulmonary fibrosis

Respiratory Research, 2018
Background Since 2009, IPF patients across Europe are recruited into the eurIPFreg, providing epidemiological data and biomaterials for translational research.
Andreas Guenther, Ekaterina Krauss, Silke Tello, Jasmin Wagner, Bettina Paul, Stefan Kuhn, Olga Maurer, Sabine Heinemann, Ulrich Costabel, María Asunción Nieto Barbero, Veronika Müller, Philippe Bonniaud, Carlo Vancheri, Athol Wells, Martina Vasakova, Alberto Pesci, Matteo Sofia, Walter Klepetko, Werner Seeger, Fotios Drakopanagiotakis, Bruno Crestani   +20 more
doaj   +1 more source

Current Status, Challenges, Policies, and Bioethics of Biobanks [PDF]

Genomics & Informatics, 2013
Many biobanks were established as biorepositories for biomedical research, and a number of biobanks were founded in the 1990s. The main aim of the biobank is to store and to maintain biomaterials for studying chronic disease, identifying risk factors of ...
Byunghak Kang, Jaesun Park, Sangyun Cho, Meehee Lee, Namhee Kim, Haesook Min, Sooyoun Lee, Ok Park, Bokghee Han   +8 more
doaj   +1 more source

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

PLoS Medicine, 2015
Cathie Sudlow and colleagues describe the UK Biobank, a large population-based prospective study, established to allow investigation of the genetic and non-genetic determinants of the diseases of middle and old age.
C. Sudlow, J. Gallacher, N. Allen, V. Beral, P. Burton, J. Danesh, P. Downey, P. Elliott, J. Green, M. Landray, Bette Liu, P. Matthews, G. Ong, J. Pell, A. Silman, Alan Young, Tim Sprosen, T. Peakman, R. Collins   +18 more
semanticscholar   +1 more source

Advanced Omics and Radiobiological Tissue Archives: The Future in the Past

Applied Sciences, 2021
Archival formalin-fixed, paraffin-embedded (FFPE) tissues and their related diagnostic records are an invaluable source of biological information. The archival samples can be used for retrospective investigation of molecular fingerprints and biomarkers ...
Omid Azimzadeh, Maria Gomolka, Mandy Birschwilks, Shin Saigusa, Bernd Grosche, Simone Moertl   +5 more
doaj   +1 more source

Biobanks and biobank networks [PDF]

, 2019
Peer ...
Ortega-Paino, Eva, Tupasela, Aaro
openaire   +2 more sources

Access to Biobanks: Harmonization Across Biobank Initiatives [PDF]

Biopreservation and Biobanking, 2014
The current study investigates whether access arrangements relevant for biobanking contain clear information on key access conditions. It furthermore assesses the extent to which these access conditions are harmonized across biobank initiatives.A comparative analysis was conducted of access arrangements developed by 26 organizations, 36 biobank ...
Michiel, Verlinden, Herman, Nys, Nadine, Ectors, Isabelle, Huys   +3 more
openaire   +3 more sources

Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort [PDF]

, 2018
Background: There is strong evidence that people born in winter and in spring have a small increased risk of schizophrenia. As this ‘season of birth’ effect underpins some of the most influential hypotheses concerning potentially modifiable risk ...
Escott-Price, Valentina, Kendall, Kimberley, Kirov, George, O'Donovan, Michael C., Owen, Michael J., Smith, Daniel J., Walters, James, Ward, Joey   +7 more
core   +3 more sources

Russian Biodiversity Collections: A Professional Opinion Survey

Animals, 2023
Biodiversity collections are important vehicles for protecting endangered wildlife in situations of adverse anthropogenic influence. In Russia, there are currently a number of institution- and museum-based biological collections, but there are no nation ...
Elena V. Alpeeva, Natalia P. Sharova, Konstantin S. Sharov, Ekaterina A. Vorotelyak   +3 more
doaj   +1 more source