Results 41 to 50 of about 99,905 (246)
Importance of Human Faecal Biobanking: From Collection to Storage
Postępy MikrobiologiiThe freezing and storage conditions of faecal samples in biobanks influence the preservation of the integrity and stability of genetic material and play a crucial role in scientific and clinical research quality.
Lewandowska Izabela +2 more
doaj +1 more source
How the world of biobanking is changing with artificial intelligence
Frontiers in Digital HealthArtificial Intelligence is increasingly shaping the practice of biobanking by influencing how biobanks evolve and operate, especially when it concerns their relationship to data.
Michaela Th. Mayrhofer +1 more
doaj +1 more source
Bioresource from the French Gazel Cohort Study
Open Journal of Bioresources, 2014 The GAZEL Cohort Study set up in 1989 is a general-purpose epidemiologic cohort. At inception in 1989, the cohort included 20,625 volunteers then aged from 35-50 (women; n= 5,614) or 40-50 (men; n= 15,011).
Marcel Goldberg +3 more
doaj +1 more source
Frontiers in Genetics, 2021 Following the successful creation of a biobank from two adult Thoroughbred mares, this study aimed to recapitulate sample collection in two adult Thoroughbred stallions as part of the Functional Annotation of the Animal Genome (FAANG) initiative.
Callum G. Donnelly +21 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
BiomedicinesBackground: Hereditary breast and ovarian cancer is an inherited condition caused by pathogenic (P) or likely pathogenic (LP) variants in the BRCA1 and BRCA2 genes.
Salha Bujassoum Al Bader +15 more
doaj +1 more source
Frontiers in Medicine, 2019 Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory condition affecting mainly the gastro-intestinal tract with two main entities: Crohn's disease (CD) and ulcerative colitis (UC).
Isabelle Cleynen +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source