Results 41 to 50 of about 220,549 (336)
Frontiers in Medicine, 2023 BackgroundBiobanks are essential structures for scientific research. The RHINEVIT biobank is used to recruit biomaterials from rheumatology patients in outpatient care and to conduct clinical research studies (e.g., cohort studies) and basic research ...
Jutta G. Richter +19 more
doaj +1 more source
HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation [PDF]
, 2018 Background HIV-infected subjects with suboptimal CD4 restoration despite suppressive combined antiretroviral treatment (cART) (immunodiscordant subjects) have been classically characterized after a variable period of time under cART.
Genebat González, Miguel +10 more
core +1 more source
Clinical biomarker-based biological aging and risk of cancer in the UK Biobank
British Journal of Cancer, 2023 Despite a clear link between aging and cancer, there has been inconclusive evidence on how biological age (BA) may be associated with cancer incidence. We studied 308,156 UK Biobank participants with no history of cancer at enrolment.
Jonathan K. L. Mak +6 more
semanticscholar +1 more source
Nature Communications, 2020 UK Biobank is a population-based cohort of half a million participants aged 40–69 years recruited between 2006 and 2010. In 2014, UK Biobank started the world’s largest multi-modal imaging study, with the aim of re-inviting 100,000 participants to ...
T. Littlejohns +23 more
semanticscholar +1 more source
Mexican Biobank advances population and medical genomics of diverse ancestries
Nature, 2023 Latin America continues to be severely underrepresented in genomics research, and fine-scale genetic histories and complex trait architectures remain hidden owing to insufficient data^ 1 .
M. Sohail +28 more
semanticscholar +1 more source
Relationships between estimated autozygosity and complex traits in the UK Biobank [PDF]
, 2018 Inbreeding increases the risk of certain Mendelian disorders in humans but may also reduce fitness through its effects on complex traits and diseases. Such inbreeding depression is thought to occur due to increased homozygosity at causal variants that ...
Evans, Luke M +2 more
core +5 more sources
Risk Factors for Young-Onset Dementia in the UK Biobank.
JAMA Neurology, 2023 Importance There is limited information on modifiable risk factors for young-onset dementia (YOD). Objective To examine factors that are associated with the incidence of YOD.
Stevie Hendriks +7 more
semanticscholar +1 more source
Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study [PDF]
, 2017 OBJECTIVE Grip strength and diabetes are predictors of mortality and cardiovascular disease (CVD), but whether these risk factors interact to predispose to adverse health outcomes is unknown.
Anderson, Jana +12 more
core +1 more source
Open Journal of Bioresources, 2014 Urolithiasis is frequent and raises significant health care burden in a working-age population. Its prevalence, in the Azores archipelago, is currently unknown but it is thought to be higher than the overall estimated prevalence.
Bruna Parreira +7 more
doaj +1 more source
Complex Feline Disease Mapping Using a Dense Genotyping Array
Frontiers in Veterinary Science, 2022 The current feline genotyping array of 63 k single nucleotide polymorphisms has proven its utility for mapping within breeds, and its use has led to the identification of variants associated with Mendelian traits in purebred cats.
Isabel Hernandez +27 more
doaj +1 more source