Results 61 to 70 of about 220,549 (336)

Association between active commuting and incident cardiovascular disease, cancer, and mortality: prospective cohort study [PDF]

, 2017
Objective: To investigate the association between active commuting and incident cardiovascular disease (CVD), cancer, and all cause mortality. Design: Prospective population based study. Setting: UK Biobank.
Anderson, Jana, Celis-Morales, Carlos A., Gill, Jason M.R., Guo, Yibing, Lyall, Donald M., Mackay, Daniel F., Maldonado, Reno, Pell, Jill P., Sattar, Naveed, Steell, Lewis, Welsh, Paul   +10 more
core   +1 more source

Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis

British medical journal, 2020
Objective To compare established associations between risk factors and mortality in UK Biobank, a study with an exceptionally low rate of response to its baseline survey, against those from representative studies that have conventional response rates ...
G. Batty, C. Gale, M. Kivimäki, I. Deary, S. Bell   +4 more
semanticscholar   +1 more source

Commercialisation fears and preferred forms of governance: a mixed methods investigation to identify a trusted Australian genomics repository

Frontiers in Public Health
This study aimed to identify operating conditions and governance mechanisms that would help to facilitate trust in, and willingness to donate to, a hypothetical Australian national genomic repository for health research where commercial use of data is ...
Brad Elphinstone, Jarrod Walshe, Dianne Nicol, Mark Taylor   +3 more
doaj   +1 more source

Living biobank-based cancer organoids: prospects and challenges in cancer research

Cancer Biology & Medicine, 2022
Biobanks bridge the gap between basic and translational research. Traditional cancer biobanks typically contain normal and tumor tissues, and matched blood. However, biospecimens in traditional biobanks are usually nonrenewable.
Haixin Li, Hongkun Liu, Kexin Chen
doaj   +1 more source

Self-Reported Facial Pain in UK Biobank Study : Prevalence and Associated Factors [PDF]

, 2014
Peer ...
Beasley, Marcus, Macfarlane, Gary J, MacFarlane, Tatiana   +2 more
core   +1 more source

The sequences of 150,119 genomes in the UK Biobank

Nature, 2021
Detailed knowledge of how diversity in the sequence of the human genome affects phenotypic diversity depends on a comprehensive and reliable characterization of both sequences and phenotypic variation.
B. Halldórsson, H. Eggertsson, K. Moore, Hannes Hauswedell, Ogmundur Eiriksson, M. Ulfarsson, G. Pálsson, Marteinn T. Hardarson, A. Oddsson, B. Jensson, Snaedis Kristmundsdottir, Brynja D. Sigurpálsdóttir, Olafur A. Stefansson, Doruk Beyter, Guillaume Holley, V. Tragante, Arnaldur Gylfason, Pall I. Olason, Florian Zink, Margret Asgeirsdottir, Sverrir T. Sverrisson, Brynjar Sigurdsson, S. A. Gudjonsson, Gunnar Sigurdsson, G. Halldorsson, G. Sveinbjornsson, K. Norland, U. Styrkársdóttir, Droplaug N. Magnúsdóttir, S. Snorradóttir, Kari Kristinsson, Emilia Sobech, H. Jonsson, Á. Geirsson, I. Olafsson, Pálmi V. Jónsson, O. Pedersen, C. Erikstrup, S. Brunak, S. Ostrowski, G. Thorleifsson, F. Jónsson, P. Melsted, I. Jónsdóttir, T. Rafnar, H. Hólm, H. Stefánsson, J. Saemundsdottir, D. Gudbjartsson, O. Magnusson, G. Másson, U. Thorsteinsdóttir, Agnar Helgason, Hákon Jónsson, P. Sulem, K. Stefánsson   +55 more
semanticscholar   +1 more source

Justice and the Pandemic City: How the Pandemic Has Revealed Social, Urban, and Data Injustices, and How a Narrative Approach Can Unlock Them

Frontiers in Sustainable Cities, 2022
The global COVID-19 pandemic has exacerbated infrastructural, societal, and resource inequalities along racial and socioeconomic lines. Many countries have struggled to provide adequate COVID testing and healthcare.
Natalie Marie Gulsrud, Henriette Steiner
doaj   +1 more source

Ethnic specific obesity cut-offs for diabetes risk: cross-sectional study of 490, 288 UK Biobank participants [PDF]

, 2014
OBJECTIVE To compare the relationship between adiposity and prevalent diabetes across ethnic groups in the UK Biobank cohort and to derive ethnic-specific obesity cutoffs that equate to those developed in white populations in terms of diabetes prevalence.
Gill, Jason, Mackay, Daniel, Ntuk, Uduakobong, Pell, Jill, Sattar, Naveed   +4 more
core   +1 more source

Prospective study design and data analysis in UK Biobank

Science Translational Medicine
Population-based prospective studies, such as UK Biobank, are valuable for generating and testing hypotheses about the potential causes of human disease.
Naomi E. Allen, Ben Lacey, D. A. Lawlor, Jill P. Pell, John Gallacher, L. Smeeth, P. Elliott, P. Matthews, R. Lyons, Anthony D. Whetton, Anneke Lucassen, M. Hurles, Michael Chapman, Andrew W. Roddam, Natalie K. Fitzpatrick, Anna L. Hansell, Rebecca Hardy, R. Marioni, Valerie B. O’Donnell, Julie Williams, Cecilia M. Lindgren, Mark Effingham, J. Sellors, J. Danesh, R. Collins   +24 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source