Results 81 to 90 of about 171,678 (355)

Mexican Biobank advances population and medical genomics of diverse ancestries

Nature, 2023
Latin America continues to be severely underrepresented in genomics research, and fine-scale genetic histories and complex trait architectures remain hidden owing to insufficient data^ 1 .
M. Sohail, María J. Palma-Martínez, A. Chong, C. D. Quinto-Cortés, Carmina Barberena-Jonas, Santiago G. Medina-Muñoz, Aaron P. Ragsdale, Guadalupe Delgado-Sánchez, L. Cruz-Hervert, Leticia Ferreyra-Reyes, E. Ferreira-Guerrero, Norma Mongua-Rodríguez, Sergio Canizales-Quintero, A. Jiménez-Kaufmann, H. Moreno-Macías, C. Aguilar-Salinas, K. Auckland, A. Cortes, V. Acuña-Alonzo, Chris Gignoux, G. Wojcik, A. Ioannidis, Selene L. Fernandez-Valverde, A. Hill, M. Tusié-Luna, A. Mentzer, J. Novembre, L. García-García, A. Moreno-Estrada   +28 more
semanticscholar   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Inflammatory Bowel Disease (IBD)—A Textbook Case for Multi-Centric Banking of Human Biological Materials

Frontiers in Medicine, 2019
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory condition affecting mainly the gastro-intestinal tract with two main entities: Crohn's disease (CD) and ulcerative colitis (UC).
Isabelle Cleynen, Loes Linsen, Sare Verstockt, Bram Verstockt, Vera Ballet, Eline Vandeput, Gert Van Assche, Marc Ferrante, Marc Ferrante, Kristel Van Landuyt, Séverine Vermeire, Séverine Vermeire, Nadine Ectors   +12 more
doaj   +1 more source

Generation of a Biobank From Two Adult Thoroughbred Stallions for the Functional Annotation of Animal Genomes Initiative

Frontiers in Genetics, 2021
Following the successful creation of a biobank from two adult Thoroughbred mares, this study aimed to recapitulate sample collection in two adult Thoroughbred stallions as part of the Functional Annotation of the Animal Genome (FAANG) initiative.
Callum G. Donnelly, Rebecca R. Bellone, Rebecca R. Bellone, Erin N. Hales, Annee Nguyen, Scott A. Katzman, Ghislaine A. Dujovne, Kelly E. Knickelbein, Felipe Avila, Ted S. Kalbfleisch, Elena Giulotto, Nicole B. Kingsley, Jocelyn Tanaka, Elizabeth Esdaile, Sichong Peng, Anna Dahlgren, Anna Fuller, Michael J. Mienaltowski, Terje Raudsepp, Verena K. Affolter, Jessica L. Petersen, Carrie J. Finno   +21 more
doaj   +1 more source

Biobank@VITO: Biobanking the General Population in Flanders

Frontiers in Medicine, 2020
During the last 15 years, VITO has established an infrastructure for biobanking a collection of biological samples from the general population in Flanders (Belgium). This biobank was set up to contribute to future, yet unspecified, research questions in the field of environment and health.
Rosette Van Den Heuvel, Elly Den Hond, Ann Colles, Vera Nelen, Karen Van Campenhout, Greet Schoeters   +5 more
openaire   +3 more sources

Epidemiology of neuropathic pain: an analysis of prevalence and associated factors in UK Biobank

PAIN Reports, 2023
Supplemental Digital Content is Available in the Text. An analysis of UK Biobank participants who completed a detailed pain questionnaire identified factors associated with neuropathic pain (NeuP) vs no chronic pain and non-NeuP and estimated the ...
G. Baskozos, H. Hébert, Mathilde M V Pascal, A. Themistocleous, G. Macfarlane, D. Wynick, David L H Bennett, Blair H. Smith   +7 more
semanticscholar   +1 more source

UK Biobank Motor Neurone Disease (MND) phenotype

, 2019
UK Biobank Motor Neurone Disease (MND ...
UK Biobank Outcome Adjudication Group (7239638), John Nolan (3432041), Kathryn Bush (7239637), Cathie Sudlow (259959)   +3 more
core   +1 more source

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.

, 2021
Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is used to diagnose and manage ophthalmic diseases including glaucoma.
Mark J Simcoe, David A Mackey, Cornelia M van Duijn, Chris J Hammond, UK Biobank Eye and Vision Consortium, Janey L Wiggs, Hewitt, Alex W., Hélène Choquet, Jamie Craig, Choquet, Hélène, Fitzgerald, Tomas W., Denize Atan, Pasquale, Louis R., Powell, Joseph E., Craig, Jamie, Patel, Praveen J., van Duijn, Cornelia M., Currant, Hannah, Pirro Hysi, Seyhan Yazar, Kubo, Michiaki, Charng, Jason, Reisman, Charles A., Mackey, David A, Khawaja, Anthony P., Hewitt, Alex W, Jue-Sheng Ong, Ong, Jue-Sheng, Alberta A H J Thiadens, Pasquale, Louis R, Alex W Hewitt, Reisman, Charles A, Hammond, Chris J., Fitzgerald, Tomas W, Caroline C W Klaver, Bonnemaijer, Pieter WM, International Glaucoma Genetics Consortium, Joseph E Powell, Pieter W M Bonnemaijer, Hysi, Pirro, Patel, Praveen J, Anne Senabouth, Tin Aung, Klaver, Caroline CW, Powell, Joseph E, Wiggs, Janey L., Simcoe, Mark J., Ewan Birney, Atan, Denize, Maciej Daniszewski, Louis R Pasquale, Praveen J Patel, Simcoe, Mark J, Birney, Ewan, Alice Pébay, Gharahkhani, Puya, Mackey, David A., Thiadens, Alberta AHJ, Hammond, Chris J, Bonnemaijer, Pieter W.M., Stuart MacGregor, Senabouth, Anne, Foster, Paul J, Ong, Jue Sheng, Charles A Reisman, Jason Charng, van Duijn, Cornelia M, Eric Jorgenson, Khawaja, Anthony P, Klaver, Caroline C.W., Peng T Khaw, Foster, Paul J., Yazar, Seyhan, Anthony P Khawaja, Aung, Tin, Khaw, Peng T., Khaw, Peng T, Wiggs, Janey L, Thiadens, Alberta A.H.J., Paul J Foster, Jorgenson, Eric, MacGregor, Stuart, Puya Gharahkhani, Tomas W Fitzgerald, Daniszewski, Maciej, Pébay, Alice, Michiaki Kubo, Hannah Currant   +87 more
core   +1 more source

The Sri Lankan twin registry biobank: South Asia's first twin biobank [PDF]

, 2020
Introduction: Biobanks are a valuable resource for creating advancements in science through cutting-edge omics research. Twin research methods allow us to understand the degree to which genetics and environmental factors contribute to health outcomes ...

core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source