Results 91 to 100 of about 147,982 (310)

An ELISA for apolipoprotein M reveals a strong correlation to total cholesterol in human plasma

Journal of Lipid Research, 2007
Apolipoprotein M (apoM) is a 188 amino acid, 25 kDa protein belonging to the lipocalin protein superfamily. Although predominantly associated with high density lipoprotein, apoM is found in all major lipoprotein classes. To facilitate clinical studies of
Olof Axler, Josefin Ahnström, Björn Dahlbäck   +2 more
doaj   +1 more source

Evaluation of RNA purification methods by using different blood stabilization tubes: identification of key features for epidemiological studies

BMC Research Notes, 2020
Objective Peripheral blood is the most promising source of RNA biomarkers for diagnostic and epidemiological studies, because the presence of disease and prognostic information is reflected in the gene expression pattern.
J. A. Carrillo-Ávila, R. de la Puente, P. Catalina, J. D. Rejón, L. Espín-Vallejo, V. Valdivieso, R. Aguilar-Quesada   +6 more
doaj   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Planning Today for Tomorrow’s Research: Analysis of Factors Influencing Participation in a Pediatric Cancer Research Biorepository

Frontiers in Oncology, 2018
BackgroundBiobanks have become a powerful tool that fosters biomedical research. The success of biobanks depends upon people’s perception and willingness to donate their samples for research.
Rania M. Labib, Omneya Hassanain, Maram Alaa, Safaa Ahmed, Sherif Abou El-Naga   +4 more
doaj   +1 more source

The Sciensano biobanks before, during and after the COVID-19 pandemic: challenges and opportunities

, 2023
All Sciensano biobanks were installed conform to the biobank legislation of 2018. This in order to keep preserving and using Sciensano’s existing and future collections of human body material for scientific research, mainly in the domain of infectious ...
A. Vodolazkaia, D. Triest, K. Dierick, K.Espinoza Rimachi, P. Pauss   +4 more
core  

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Use of the ACP® and BTS extenders for cooling at 15°C white-lipped peccary (Tayassu pecari) semen

Pesquisa Veterinária Brasileira
: Knowledge about reproduction of white-lipped peccary is of great importance to assist with the conservation of this species and enable its rational use in captivity.
Celso H.S.C. Barros, William M. Machado, Renan L.A. Vieira, Ivan B. Allaman, Sérgio L.G. Nogueira-Filho, Rodrigo F. Bittencourt, Paola P.N. Snoeck   +6 more
doaj   +1 more source

Hypothetical and factual willingness to participate in biobank research

, 2010
In the debate on biobank regulation, arguments often draw upon findings in surveys on public attitudes. However, surveys on willingness to participate in research may not always predict actual participation rates.
Stefan Eriksson, Mats G Hansson, Hansson, Mats G, Hansson, M.G., Eriksson, Stefan, Ingibjorg Halldorsdottir, Eriksson, S., Halldorsdottir, Ingibjörg, Helgesson, Gert,, Eriksson, Stefan,, Hansson, Mats G.,, Rafnar, Thorunn, Halldorsdottir, I., Chia, Kee-Seng,, Chia, Kee-Seng, Thorunn Rafnar, Helgesson, G., Johnsson, L., Rafnar, Thorunn,, Kee-Seng Chia, Rafnar, T., Chia, K.-S., Johnsson, Linus, Hansson, Mats G., Gert Helgesson, Helgesson, Gert, Linus Johnsson, Halldorsdottir, Ingibjörg,, Kee-Seng, Chia, Johnsson, Linus,   +29 more
core   +1 more source

Whole-Exome Imputation Within UK Biobank Powers Rare Coding Variant Association and Fine-Mapping Analyses

, 2023
Exome association studies to date have generally been underpowered to systematically evaluate the phenotypic impact of very rare coding variants. We leveraged extensive haplotype sharing between 49,960 exome-sequenced UK Biobank participants and the ...
Loh, Po-Ru, Barton, Alison R., Sherman, Maxwell A., Mukamel, Ronen E.   +3 more
core   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source