Results 91 to 100 of about 171,678 (355)

Importance of Human Faecal Biobanking: From Collection to Storage

open access: yesPostępy Mikrobiologii
The freezing and storage conditions of faecal samples in biobanks influence the preservation of the integrity and stability of genetic material and play a crucial role in scientific and clinical research quality.
Lewandowska Izabela   +2 more
doaj   +1 more source

How the world of biobanking is changing with artificial intelligence

open access: yesFrontiers in Digital Health
Artificial Intelligence is increasingly shaping the practice of biobanking by influencing how biobanks evolve and operate, especially when it concerns their relationship to data.
Michaela Th. Mayrhofer   +1 more
doaj   +1 more source

Reweighting UK Biobank corrects for pervasive selection bias due to volunteering

open access: yesInternational Journal of Epidemiology
Background Biobanks typically rely on volunteer-based sampling. This results in large samples (power) at the cost of representativeness (bias). The problem of volunteer bias is debated.
S. van Alten   +4 more
semanticscholar   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

From Biobank to Bedside: A Pilot Study on Returning Medically Actionable BRCA1/2 Results in Qatar’s Precision Medicine Landscape

open access: yesBiomedicines
Background: Hereditary breast and ovarian cancer is an inherited condition caused by pathogenic (P) or likely pathogenic (LP) variants in the BRCA1 and BRCA2 genes.
Salha Bujassoum Al Bader   +15 more
doaj   +1 more source

Blood protein assessment of leading incident diseases and mortality in the UK Biobank

open access: yesNature Aging
The circulating proteome offers insights into the biological pathways that underlie disease. Here, we test relationships between 1,468 Olink protein levels and the incidence of 23 age-related diseases and mortality in the UK Biobank (n = 47,600).
D. Gadd   +13 more
semanticscholar   +1 more source

Occupation and risk of severe COVID-19: prospective cohort study of 120,075 UK Biobank participants

open access: yesOccupational and Environmental Medicine, 2020
Objectives To investigate severe COVID-19 risk by occupational group. Methods Baseline UK Biobank data (2006–10) for England were linked to SARS-CoV-2 test results from Public Health England (16 March to 26 July 2020). Included participants were employed
M. Mutambudzi   +20 more
semanticscholar   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A low-tech, cost-effective and efficient method for safeguarding genetic diversity by direct cryopreservation of poultry embryonic reproductive cells

open access: yeseLife, 2022
Chickens are an important resource for smallholder farmers who raise locally adapted, genetically distinct breeds for eggs and meat. The development of efficient reproductive technologies to conserve and regenerate chicken breeds safeguards existing ...
Tuanjun Hu   +8 more
doaj   +1 more source

Biobank networking and globalisation: perspectives and practices of Australian biobanks

open access: yesAustralian Health Review, 2020
Objective This study examined the practices and attitudes of Australian biobanks regarding access to samples and data, as well as local and global networking with other biobanks. Methods This was a mixed-methods study, including an ...
Edwina Light   +8 more
openaire   +6 more sources

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