Results 101 to 110 of about 31,338 (290)

Imaging biobanks: operational limits, medical-legal and ethical reflections

Frontiers in Digital Health
The extraordinary growth of health technologies has determined an increasing interest in biobanks that represent a unique wealth for research, experimentation, and validation of new therapies.
Emanuele Capasso, Claudia Casella, Mariagrazia Marisei, Mario Tortora, Francesco Briganti, Pierpaolo Di Lorenzo   +5 more
doaj   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

Arthritis Care &Research, EarlyView.
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard, Cammie Tran, Hans G. Schneider, Flavia M. Cicuttini, Anita E. Wluka, Ego Seeman, Johannes T. Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P. Q. Clark, Daniel Clayton‐Chubb, Andrew M. Tonkin, Lawrence J. Beilin, Robyn L. Woods, John J. McNeil   +15 more
wiley   +1 more source

Intellectual Property, Open Science and Research Biobanks [PDF]

, 2014
In biomedical research and translational medicine, the ancient war between exclusivity (private control over information) and access to information is proposing again on a new battlefield: research biobanks. The latter are becoming increasingly important
A Boggiano, A Cambon-Thomsen, A De Robbio, A De Robbio, A Delfanti, A Grafton, A J Kinney, A M Edwards, A Nicol, A Plant, A Rai, A S Kesselheim, A Torrance, Aa Vv, Andreoli Versbach, B Booth, B Burrow, B Corian, B Fecher, B P Lucey, Boyle, C Borgman, C Hess, C Hess, D C Mowery, D C Mowery, D Gitter, D Mowery, D Nichols, D Winickoff, De Beer, De Castro, Destro Bisol, E Campbell, E Hippel Von, E Hippel Von, E Kitch, E Raymond, E Roppo, E S Dove, Engl, F Collins, F Michelman, F Murray, F Parisi, Federica Giovanella, Francesco Planchenstainer, Francesco Planchestainer, G Alpa, G Annas, G Fitzgerald, G Frosio, G Hardin, G Javitt, G Parchomovsky, G Resta, G Van Overwalle, Giovanni Pascuzzi, Giovanni Pascuzzi, Giuseppe Bellantuono, H Chesbrough, H Hipkens, H Landecker, J Boyle, J Boyle, J Boyle, J Derry, J Gu�don, J H Reichman, J H Reichman, J Hope, J Kaye, J Lerner, J Lunshof, J M Conley, J Weigelt, J Willinsky, K Ku, K Noonan, L Lessig, L Lessig, M A Heller, M Enserink, M Granieri, M Heller, M Heller, M J Madison, M Macilotti, M Paganelli, M Perkmann, M Tomasson, Mass Cambridge, N Dietr, N Kranich, Nelson R R, P Cuatrecasas, P Dasgupta, P Guarda, P Manghi, P Menell, P Samuelson, P Suber, P Suber, Paolo Guarda, R Caso, R Caso, R Ducato, R E Gold, R Feldman, R Feldman, R Gold, R Mazzoleni, R Merges, R Merges, R Solow, R Stallman, R Summit, Roberto Caso, Roberto Caso, Roberto Caso, Roberto Caso, Roberto Caso, Roberto Caso, Roberto Caso, Roberto Caso, Rossana Ducato, Rossana Ducato, S Boettinger, S Chakravarty, S Harnad, S Ladas, S Maurer, S Shapin, S Strauss, Springer Heidelberg, Springer Heidelberg, T Margoni, Thomas Margoni, Umberto Izzo, Umberto Izzo, Umberto Izzo, V Rodriguez, Valentina Moscon, W D Streitz, W M Landes, W Nordhaus, X Schildwachter, Z Lei   +147 more
core   +1 more source

Accuracy of Diagnostic Codes and Algorithms Used to Identify Rheumatoid Arthritis and Juvenile Idiopathic Arthritis in Administrative Claims and Electronic Health Records: Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in electronic health records. Methods We searched Medline, Embase, and Cochrane Central Register for Controlled Trials databases and included studies that validated case definitions against a ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Population’s perspectives toward biobanks in scientific research: a study from Jordan

Pharmacogenomics and Personalized Medicine, 2019
Hanin Makhlouf,1 Nasr Alrabadi,2 Omar F Khabour,1 Karem H Alzoubi,3 Wael Al-Delaimy4 1Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Pharmacology, Faculty of Medicine, Jordan ...
Makhlouf H, Alrabadi N, Khabour OF, Alzoubi KH, Al-Delaimy W   +4 more
doaj  

DNA, Data and Ethics [PDF]

, 2006
The biophysical differences between different kinds of DNA data banks are described. The different ethical implications of DNA fingerprint data banks, data banks of known gene sequences, and data banks of total genomic sequences are considered.
Stewart, J.A.
core  

Data sharing: What about epidemiological cohorts? [PDF]

, 2011
General-purpose population-based cohorts can be powerful scientific platforms. The Gazel Cohort Study, a French cohort of 20,000 adults followed-up since more than 20 years, was designed as an open epidemiologic laboratory, hosting more than 40 nested ...
Marcel Goldberg, Marie Zins
core   +2 more sources

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

Arthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A Mamas   +8 more
wiley   +1 more source

2011 Strategic roadmap for Australian research infrastructure [PDF]

The 2011 Roadmap articulates the priority research infrastructure areas of a national scale (capability areas) to further develop Australia’s research capacity and improve innovation and research outcomes over the next five to ten years.
Department of Innovation, Industry, Science and Research   +2 more
core