Results 41 to 50 of about 31,631 (243)

Setting up clinical and production-based biobanks in the healthcare system of the Russian Federation

Трансплантология (Москва)
Background. The therapeutic efficacy of skin grafts and various tissue equivalents in the treatment of many diseases is known. Special clinical biobanks are engaged in the procurement of such products, their processing, storage, provision of their safety
Yu. N. Lebedeva, Yu. V. Sukhanov, E. M. Fominykh, A. V. Eremeev, O. S. Rogovaya, T. A. Aleksanyan, E. A. Vorotelyak, A. V. Vasiliev   +7 more
doaj   +1 more source

Introduction : biofutures/biopresents [PDF]

, 2006
Two very different reports produced for the UK government in the last three years have connected the state of our physical health with that of our material wealth. The first of these was produced in 2003 by the Bioscience Innovation and Growth Team (BIGT)
Birch, Kean
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Public awareness, attitudes, and motivation toward biobanks: a survey of China

BMC Medical Ethics
Background Biobanks are vital for advancing medical research, and public participation is a crucial determinant of their success. This study uses a survey to assess the awareness, attitudes, and motivation of the public in China with regard to ...
Mingtao Huang, Lanyi Yu, Xiaonan Wang, Kun Li, Jichao Wang, Xinrui Cheng, Xiaomei Zhai   +6 more
doaj   +1 more source

Public trust and global biobank networks

BMC Medical Ethics, 2020
Background Biobanks provide an important foundation for genomic and personalised medicine. In order to enhance their scientific power and scope, they are increasingly becoming part of national or international networks.
Lisa Dive, Christine Critchley, Margaret Otlowski, Paul Mason, Miriam Wiersma, Edwina Light, Cameron Stewart, Ian Kerridge, Wendy Lipworth   +8 more
doaj   +1 more source

Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future [PDF]

, 2016
Metabolomics and lipidomics are emerging methods for detailed phenotyping of small molecules in samples. It is hoped that such data will: (i) enhance baseline prediction of patient response to pharmacotherapies (beneficial or adverse); (ii) reveal ...
Preiss, David, Rankin, Naomi J., Sattar, Naveed, Welsh, Paul   +3 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Biobanks and data interoperability in Latin America: engendering high-quality evidence for the global research ecosystem

Frontiers in Medicine
Currently, each biobank in Latin America operates with its own set of standards for database creation and management, resulting in a lack of regional and international interoperability.
Erick Valdés, Juan Alberto Lecaros
doaj   +1 more source

The UCLA ATLAS Community Health Initiative: Promoting precision health research in a diverse biobank

Cell Genomics, 2023
Summary: The UCLA ATLAS Community Health Initiative (ATLAS) has an initial target to recruit 150,000 participants from across the UCLA Health system with the goal of creating a genomic database to accelerate precision medicine efforts in California. This
Ruth Johnson, Yi Ding, Arjun Bhattacharya, Sergey Knyazev, Alec Chiu, Clara Lajonchere, Daniel H. Geschwind, Bogdan Pasaniuc   +7 more
doaj   +1 more source

Biobank Economics and the “Commercialization Problem” [PDF]

, 2013
The economic aspects of biobanking are intertwined with the social and scientific aspects. We describe two problems that structure the discussion about the economics of biobanking and which illustrate this intertwining.
Dallaire-Fortier, Clara, Murtagh, Madeleine J, Turner, Andrew   +2 more
core   +3 more sources