Results 161 to 170 of about 47,461 (243)

On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily

Angewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.
Comprehensive analyses of two enzyme classes from the amidohydrolase superfamily (AHS) revealed that catalysis proceeds either via 1,4 or 1,6 nucleophilic conjugate addition and that this property defines substrate specificity. Moreover, although all substrates and products are entirely achiral, this mechanistic difference results in an inverted ...
Lukas Drexler, Torben F. Fürtges, Till Rudack, Reinhard Sterner   +3 more
wiley   +1 more source

Argonaute-mediated RNA editing selectively repairs point mutations. [PDF]

Nucleic Acids Res
Zhang Z, Wang J, Guo T, Yu X, Wang F, Zhang H, Liu Y, Li W, Cheng Y, Peng Y, Yan G, Cui J, Ma L.   +12 more
europepmc   +1 more source

Asymmetric Catalytic Hydrogenation toward a Value‐Added Chiral Building Block: Optically Active γ‐Butyrolactone Scaffold from Renewable and Synthetic Derived Feedstocks

European Journal of Organic Chemistry, Volume 29, Issue 3, January 22, 2026.
This brief compendium summarizes the most successful asymmetric hydrogenation strategies for the preparation of chiral monocyclic γ‐lactone derivatives from keto acids and keto esters, with emphasis on their relevance for large‐scale production and high enatioselectivities. This article provides a brief compendium on the production of chiral monocyclic
Marta Feliz, Maria J. Sabater
wiley   +1 more source

Scalable and sustainable synthesis of chiral amines by biocatalysis. [PDF]

Commun Chem
Takle MJ, Maurer DM, Staehle P, Dickhaut J, Holtze C, Hellgardt K, Hii KKM.   +6 more
europepmc   +1 more source

Correction: Nanomaterial-enabled drug delivery systems for circadian medicine: bridging direct rhythm modulation and chronotherapy. [PDF]

RSC Adv
Zeeshan M, Hu J, Mao CX, Danish A, Xiong Y, Irshad MS, Dao VD, Liu Z.   +7 more
europepmc   +1 more source

Biocatalytic- and Chemoproteomic-Guided Discovery of a PHGDH Inhibitor from Chemoenzymatic-Promoted DNA-Encoded Libraries Selection Platform. [PDF]

J Am Chem Soc
Zhang Y, Lan Y, Fan R, Feng L, Wang G, Wu X, Wen L, Duan Z, Xia Y, Wang X, Zhang L, Zhou L, Tan M, Liao C, Lu X.   +14 more
europepmc   +1 more source

Molar-Scale Phenolic Acid Decarboxylation Using Thermostable Biocatalysts and Enzyme-Compatible Deep Eutectic Solvents. [PDF]

ChemSusChem
Vaupel S, Meyer LE, Domínguez de María P, Kara S.   +3 more
europepmc   +1 more source

Of Revolutions and Roadblocks: The Emerging Role of Machine Learning in Biocatalysis. [PDF]

ACS Cent Sci
Vornholt T, Stockinger P, Mutný M, Jeschek M, Nestl B, Oberdorfer G, Osuna S, Pleiss J, Welner DH, Krause A, Buller R, Ward TR.   +11 more
europepmc   +1 more source

Solid/Gas Synthesis of Isobutyl Propionate Catalyzed by Packed-Bed CalB Cross-Linked Enzyme Aggregates (CLEA). [PDF]

ACS Omega
Cruz-Martínez YA, Castillo-Araiza CO, Castillo-Rosales E, Velasco-Lozano S, Huerta-Ochoa S.   +4 more
europepmc   +1 more source

An algal Baeyer-Villiger monooxygenase is produced as an active enzyme in the cyanobacterium Synechocystis 6803 [PDF]

, 2017
Bergantino, Elisabetta
core