Results 101 to 110 of about 579,757 (320)

CAR-macrophages in solid tumors: promise, progress, and prospects

npj Precision Oncology
Chimeric antigen receptor macrophages (CAR-Ms) represent a promising frontier in immunotherapy, leveraging both innate and engineered capabilities to combat solid tumors.
Maram Alrehaili, Pedro Silva Couto, Rana Khalife, Qasim A. Rafiq   +3 more
doaj   +1 more source

Biomechanical and biochemical properties of the thoracic aorta in warmblood horses, Friesian horses, and Friesians with aortic rupture [PDF]

, 2015
Background: Thoracic aortic rupture and aortopulmonary fistulation are rare conditions in horses. It mainly affects Friesian horses. Intrinsic differences in biomechanical properties of the aortic wall might predispose this breed.
Chiers, Koen, Claeys, Erik, Delesalle, Catherine, Ducatelle, Richard, Duchateau, Luc, Famaey, Nele, Gröne, Andrea, Ploeg, Margreet, Saey, Veronique, Smoljkic, Marija, van Loon, Gunther   +10 more
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Editorial: Women in chemical engineering

Frontiers in Chemical Engineering, 2023
Lisa R. Volpatti, Diana Bernin, Giulia Bozzano, Cristina Chuck-Hernandez, Siti Shawalliah Idris, Karla Mayolo-Deloisa   +5 more
doaj   +1 more source

Taurine supplementation decreases fat accumulation by suppressing FAS and enhancing ATGL through the ATGL pathway [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Obesity leads to severe health issues like cardiovascular disease. Natural substances with anti-obesity properties are gaining attention.
Xueying Geng, Yafang Feng, Congcong Yu, Yuyang Yao, Wen Chen, Junxia Guo, Yanzhen Zhang, Jing Zhang, Shengquan Mi   +8 more
doaj   +1 more source

Identification of nonlinear lateral flow immunoassay state-space models via particle filter approach [PDF]

, 2012
This is the post-print of the Article. The official published version can be accessed from the link below - Copyright @ 2012 IEEEIn this paper, the particle filtering approach is used, together with the kernel smoothing method, to identify the state ...
Du, M, Li, Y, Liu, X, Wang, Z, Zeng, N
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Phosphate limitation enhances malic acid production on nitrogen-rich molasses with Ustilago trichophora

Biotechnology for Biofuels and Bioproducts
Background An important step in replacing petrochemical products with sustainable, cost-effective alternatives is the use of feedstocks other than, e.g., pure glucose in the fermentative production of platform chemicals.
Luca Antonia Grebe, Philipp Georg Lichtenberg, Katharina Hürter, Eva Forsten, Katharina Miebach, Jochen Büchs, Jørgen Barsett Magnus   +6 more
doaj   +1 more source

Customized microscale approach for optimizing two-phase bio-oxidations of alkanes with high reproducibility

Microbial Cell Factories, 2017
Background Numerous challenges remain to achieve industrially competitive space–time yields for bio-oxidations. The ability to rapidly screen bioconversion reactions for characterization and optimization is of major importance in bioprocess development ...
Johannes F. Kolmar, Oliver Thum, Frank Baganz   +2 more
doaj   +1 more source