Results 11 to 20 of about 557,900 (328)

Protein engineering in the computational age: An open source framework for exploring mutational landscapes in silico

open access: yesEngineering Biology, 2023
The field of protein engineering has seen tremendous expansion in the last decade, with researchers developing novel proteins with specialised functionalities for a range of uses, from drug discovery to industrial biotechnology.
Shirin Bamezai   +6 more
doaj   +1 more source

Development of a novel defined minimal medium for Gluconobacter oxydans 621H by systematic investigation of metabolic demands

open access: yesJournal of Biological Engineering, 2022
Background Historically, complex media are used for the cultivation of Gluconobacter oxydans in industry and research. Using complex media has different drawbacks like higher costs for downstream processing and significant variations in fermentation ...
Svenja Battling   +7 more
doaj   +1 more source

Biochemical engineering of 5hmdC-DNA using a Tet3 double-mutant

open access: green
Sahin H   +6 more
europepmc   +2 more sources

Energy-based Analysis of Biochemical Cycles using Bond Graphs [PDF]

open access: yes, 2014
Thermodynamic aspects of chemical reactions have a long history in the Physical Chemistry literature. In particular, biochemical cycles - the building-blocks of biochemical systems - require a source of energy to function.
Crampin, Edmund J., Gawthrop, Peter J.
core   +1 more source

On Projection-Based Model Reduction of Biochemical Networks-- Part II: The Stochastic Case [PDF]

open access: yes, 2014
In this paper, we consider the problem of model order reduction of stochastic biochemical networks. In particular, we reduce the order of (the number of equations in) the Linear Noise Approximation of the Chemical Master Equation, which is often used to ...
Anderson, James, Sootla, Aivar
core   +1 more source

Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels [PDF]

open access: yes, 2020
Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly ...
Hoey, David A.   +2 more
core   +1 more source

Thin-Film Nanocomposite Reverse Osmosis Membrane with High Flux and Antifouling Performance via Incorporating Maleic Anhydride-Grafted Graphene Oxide

open access: yesAdvances in Polymer Technology, 2022
Water flux is one of the most important performance parameters of the reverse osmosis (RO) membrane. The higher water flux means lower energy cost when treating the same volume of feed solution with membrane separation technology.
Zhongyan Chen   +5 more
doaj   +1 more source

Serum-free lentiviral vector production is compatible with medium-resident nuclease activity arising from adherent HEK293T host cells engineered with a nuclease-encoding transgene

open access: yesHeliyon, 2023
At present lentiviral vector production for cell and gene therapy commonly involves transient plasmid transfection of mammalian cells cultivated in serum-containing media and addition of exogenous nuclease to reduce host cell and plasmid DNA impurities ...
Sadfer Ali   +5 more
doaj   +1 more source

An extra dimension in protein tagging by quantifying universal proteotypic peptides using targeted proteomics [PDF]

open access: yes, 2016
The use of protein tagging to facilitate detailed characterization of target proteins has not only revolutionized cell biology, but also enabled biochemical analysis through efficient recovery of the protein complexes wherein the tagged proteins reside ...
De Sutter, Delphine   +9 more
core   +2 more sources

Systems Biology Graphical Notation: Entity Relationship language Level 1 [PDF]

open access: yes, 2009
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society would not have evolved at the same pace.
Anatoly Sorokin   +5 more
core   +3 more sources

Home - About - Disclaimer - Privacy