Results 41 to 50 of about 582,722 (287)
システム生物学のための統合解析シミュレータ WinBEST-KIT の開発 [PDF]
, 2018 Previously, I developed the biochemical reaction simulator called WinBEST-KIT (Biochemical Engineering System analyzing Tool-KIT, which runs under Microsoft Windows) for analyzing complicated biochemical reaction systems such as metabolic pathways ...
Sekiguchi, Tatsuya +2 more
core
Blind source separation methods for deconvolution of complex signals in cancer biology
, 2013 Two blind source separation methods (Independent Component Analysis and Non-negative Matrix Factorization), developed initially for signal processing in engineering, found recently a number of applications in analysis of large-scale data in molecular ...
Kairov, Ulykbek +3 more
core +1 more source
Improved split fluorescent proteins for endogenous protein labeling. [PDF]
, 2017 Self-complementing split fluorescent proteins (FPs) have been widely used for protein labeling, visualization of subcellular protein localization, and detection of cell-cell contact.
Feng, Siyu +5 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Engineering BiologyFocus on engineering biology is at the forefront of the UK government's objectives, being one of their five critical technologies (the others being quantum technologies, artifical intelligence, semiconductors, and future telecommunications), with a ...
Amy Switzer, Laima Šusta, Paul Mines
doaj +1 more source
Optimization of L-lactic acid production by fermentation of Huaimi dregs
Biotechnology & Biotechnological Equipment, 2018 Utilization of waste dregs, e.g. Huaimi dregs, is an important issue. Huaimi is a traditional Chinese medicine and 20,000 tons of dregs are annually produced. This study optimized the production of L-lactic acid through solid-state fermentation of Huaimi
Jingsheng Zhang +5 more
doaj +1 more source
Microbial Cell Factories, 2019 Background Production of 2,3-butanediol from renewable resources is a promising measure to decrease the consumption of fossil resources in the chemical industry.
Benedikt Heyman +4 more
doaj +1 more source
BMC Microbiology, 2023 Background The promising yet barely investigated anaerobic species Phocaeicola vulgatus (formerly Bacteroides vulgatus) plays a vital role for human gut health and effectively produces organic acids.
Laura Keitel +5 more
doaj +1 more source