Results 51 to 60 of about 261,713 (289)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Engineering BiologyFocus on engineering biology is at the forefront of the UK government's objectives, being one of their five critical technologies (the others being quantum technologies, artifical intelligence, semiconductors, and future telecommunications), with a ...
Amy Switzer, Laima Šusta, Paul Mines
doaj +1 more source
Optimization of L-lactic acid production by fermentation of Huaimi dregs
Biotechnology & Biotechnological Equipment, 2018 Utilization of waste dregs, e.g. Huaimi dregs, is an important issue. Huaimi is a traditional Chinese medicine and 20,000 tons of dregs are annually produced. This study optimized the production of L-lactic acid through solid-state fermentation of Huaimi
Jingsheng Zhang +5 more
doaj +1 more source
BMC Microbiology, 2023 Background The promising yet barely investigated anaerobic species Phocaeicola vulgatus (formerly Bacteroides vulgatus) plays a vital role for human gut health and effectively produces organic acids.
Laura Keitel +5 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
An SFN-YOLO-based detection method for the fermentation stage in the anaerobic digestion process
iScienceSummary: Anaerobic digestion is an effective and low-carbon approach for biomass utilization and energy recovery. To accurately determine fermentation stages and enhance process control, this paper proposes an anaerobic digestion fermentation stage ...
Peng Liu +5 more
doaj +1 more source
Interaction and Mechanism of Probiotics with Gut Flora and Immune Regulation: A Review
Shipin gongye ke-ji, 2022 Probiotics play beneficial roles in improving the host intestinal microecological balance and improving the host health level and health state. It mainly affects the host health by regulating the intestinal microbiota and participating in the immune ...
Manyu TANG +8 more
doaj +1 more source
Development of novel approaches for an in vitro colon model
, 2021 Gastrointestinal conditions and diseases have a significant impact on people, and in the past couple of decades, the number of cases related to these conditions have increased steadily.
Pandala, Narendra Goud
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source