Results 221 to 230 of about 3,189,858 (352)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Biochemical engineering nerve conduits using peptide amphiphiles.

open access: yesJournal of Controlled Release, 2012
A. Tan, Jayakumar Rajadas, A. Seifalian
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Biochemical Engineering of Surface α2–8 Polysialic Acid for Immunotargeting Tumor Cells [PDF]

open access: hybrid, 2000
Tianmin Liu   +4 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Hyperspectral technology and machine learning models to estimate the fruit quality parameters of mango and strawberry crops. [PDF]

open access: yesPLoS One
Elsayed S   +8 more
europepmc   +1 more source

Engineering a nanoscale liposome-in-liposome for in situ biochemical synthesis and multi-stage release [PDF]

open access: hybrid
Colin P. Pilkington   +4 more
openalex   +1 more source

Home - About - Disclaimer - Privacy