Results 31 to 40 of about 557,900 (328)
Biochemical engineering’s grand adventure
Chemical Engineering Science, 2017 Building on the recent revolution in molecular biology, enabling a wealth of bio-product innovations made from renewable feedstocks, the biotechnology field is in a transition phase to bring the products to the market. This requires a shift from natural sciences to engineering sciences with first conception of new, efficient large-scale bioprocess ...
Henk J. Noorman +2 more
openaire +4 more sources
Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model. [PDF]
, 2017 In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor.
Baar, Keith +2 more
core +2 more sources
BMC Biotechnology, 2023 Background One critical parameter in microbial cultivations is the composition of the cultivation medium. Nowadays, the application of chemically defined media increases, due to a more defined and reproducible fermentation performance than in complex ...
Jennifer Goldmanns +9 more
doaj +1 more source
Blind source separation methods for deconvolution of complex signals in cancer biology
, 2013 Two blind source separation methods (Independent Component Analysis and Non-negative Matrix Factorization), developed initially for signal processing in engineering, found recently a number of applications in analysis of large-scale data in molecular ...
Kairov, Ulykbek +3 more
core +1 more source
Reverse engineering of genetic networks with Bayesian networks [PDF]
, 2003 This paper provides a brief introduction to learning Bayesian networks from gene-expression data. The method is contrasted with other approaches to the reverse engineering of biochemical networks, and the Bayesian learning paradigm is briefly described ...
Husmeier, D.
core +1 more source
Application of the Zimm-Bragg Model to the Removal of Azo Dyes with Pectin
Adsorption Science & Technology, 2021 In this work, the ability of pectin (Pec) to remove direct red 80 (DR80), Congo red (CR), methyl orange (MO), and methyl red (MR) was studied. The removal percentages under adequate pH and ionic strength conditions were as follows: DR80 (99.5%), CR (99.8%
Juan Antonio Lozano-Álvarez +5 more
doaj +1 more source
Reduction of dynamical biochemical reaction networks in computational biology [PDF]
, 2012 Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression.
Gorban, Alexander N. +3 more
core +6 more sources
Journal of Veterinary Research, 2016 Introduction: The effects of Jin-Ying-Tang (JYT) on Toll-like Receptor 4 (TLR4) signalling transduction of lipopolysaccharide (LPS)-stimulated mouse mammary epithelial cells (MECs) in vitro were examined.
Yi Qiong +6 more
doaj +1 more source
AMB Express, 2018 Fusicocca-2,10(14)-diene (FCdiene) is a diterpene which is interesting as a precursor of the anti-cancer drug fusicoccin A and therefore for pharmaceutical applications. Production of FCdiene using a genetically modified Saccharomyces cerevisiae has been
Lisa Marie Halka +4 more
doaj +1 more source
Benchmarking biopharmaceutical process development and manufacturing cost contributions to R&D
mAbs, 2020 This study aims to benchmark and analyze the process development and manufacturing costs across the biopharmaceutical drug development cycle and their contribution to overall research and development (R&D) costs.
Suzanne S. Farid +4 more
doaj +1 more source