Results 31 to 40 of about 3,092,070 (229)

Mechanical and Biochemical Stimulation of 3D Multilayered Scaffolds for Tendon Tissue Engineering.

ACS Biomaterials Science & Engineering, 2019
Tendon injuries are frequent and occur in the elderly, young, and athletic populations. The inadequate number of donors combined with many challenges associated with autografts, allografts, xenografts, and prosthetic devices have added to the value of ...
Chiara Rinoldi, Afsoon Fallahi, Iman K. Yazdi, Jessica Campos Paras, Ewa Kijeńska‐Gawrońska, G. Trujillo‐de Santiago, Abuduwaili Tuoheti, D. Demarchi, N. Annabi, A. Khademhosseini, W. Świȩszkowski, A. Tamayol   +11 more
semanticscholar   +1 more source

Chinese herbal Jin-Ying-Tang attenuates the inflammatory response by inhibiting the activation of TLR4/MyD88/TRAF-6/NIK pathway at the mRNA level in LPS-stimulated mouse mammary epithelial cells

Journal of Veterinary Research, 2016
Introduction: The effects of Jin-Ying-Tang (JYT) on Toll-like Receptor 4 (TLR4) signalling transduction of lipopolysaccharide (LPS)-stimulated mouse mammary epithelial cells (MECs) in vitro were examined.
Yi Qiong, Li Xin, Li Yuan-Fang, Yang Hang, Zhang Xiao-Yi, Ma Zhe, Wang Lu   +6 more
doaj   +1 more source

Benchmarking biopharmaceutical process development and manufacturing cost contributions to R&D

mAbs, 2020
This study aims to benchmark and analyze the process development and manufacturing costs across the biopharmaceutical drug development cycle and their contribution to overall research and development (R&D) costs.
Suzanne S. Farid, Max Baron, Christos Stamatis, Wenhao Nie, Jon Coffman   +4 more
doaj   +1 more source

Application of the Zimm-Bragg Model to the Removal of Azo Dyes with Pectin

Adsorption Science & Technology, 2021
In this work, the ability of pectin (Pec) to remove direct red 80 (DR80), Congo red (CR), methyl orange (MO), and methyl red (MR) was studied. The removal percentages under adequate pH and ionic strength conditions were as follows: DR80 (99.5%), CR (99.8%
Juan Antonio Lozano-Álvarez, Juan Jáuregui-Rincón, Iliana E. Medina-Ramírez, Rogelio Salinas-Gutiérrez, Jorge Martín Alférez Chávez, Guadalupe Javier Araiza-Arvilla   +5 more
doaj   +1 more source

Shake flask methodology for assessing the influence of the maximum oxygen transfer capacity on 2,3-butanediol production

Microbial Cell Factories, 2019
Background Production of 2,3-butanediol from renewable resources is a promising measure to decrease the consumption of fossil resources in the chemical industry.
Benedikt Heyman, Robin Lamm, Hannah Tulke, Lars Regestein, Jochen Büchs   +4 more
doaj   +1 more source

Black glucose-releasing silicon elastomer rings for fed-batch operation allow measurement of the oxygen transfer rate from the top and optical signals from the bottom for each well of a microtiter plate

BMC Biotechnology, 2023
Background In industrial microbial biotechnology, fed-batch processes are frequently used to avoid undesirable biological phenomena, such as substrate inhibition or overflow metabolism.
Sarah Sparviero, Laura Barth, Timm Keil, Carl Dinter, Christoph Berg, Clemens Lattermann, Jochen Büchs   +6 more
doaj   +1 more source

Biochemical Stimulus-Based Strategies for Meniscus Tissue Engineering and Regeneration

BioMed Research International, 2018
Meniscus injuries are very common and still pose a challenge for the orthopedic surgeon. Meniscus injuries in the inner two-thirds of the meniscus remain incurable.
Mingxue Chen, Weimin Guo, S. Gao, C. Hao, Shih-Hwa Shen, Zengzeng Zhang, Zhenyong Wang, Zehao Wang, Xu Li, X. Jing, Xueliang Zhang, Zhiguo Yuan, Mingjie Wang, Yu Zhang, Jiang Peng, Ai-yuan Wang, Yu Wang, X. Sui, Shuyun Liu, Q. Guo   +19 more
semanticscholar   +1 more source

Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications

Military Medical Research, 2023
Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or synthetic materials, biomimetic scaffolds based on natural biomaterial can ...
Shuai Liu, Jiangming Yu, Yan-Chang Gan, Xiao-Zhong Qiu, Zhengliang Gao, Huan Wang, Shixuan Chen, Y. Xiong, Guo-hui Liu, Si-En Lin, A. McCarthy, Johnson V. John, Dai‐Xu Wei, Honghao Hou   +13 more
semanticscholar   +1 more source

Genetic Engineering: A Promising Tool to Engender Physiological, Biochemical, and Molecular Stress Resilience in Green Microalgae

Frontiers in Plant Science, 2016
As we march into the 21st century, the prevailing scenario of depleting energy resources, global warming and ever increasing issues of human health and food security will quadruple.
Freddy Guihéneuf, Asif Khan, L. Tran
semanticscholar   +1 more source

Glucose limited feed strategy leads to increased production of fusicocca-2,10(14)-diene by Saccharomyces cerevisiae

AMB Express, 2018
Fusicocca-2,10(14)-diene (FCdiene) is a diterpene which is interesting as a precursor of the anti-cancer drug fusicoccin A and therefore for pharmaceutical applications. Production of FCdiene using a genetically modified Saccharomyces cerevisiae has been
Lisa Marie Halka, Christian Nowacki, Alica Kleinschmidt, Kevin Koenen, Rolf Wichmann   +4 more
doaj   +1 more source