Results 61 to 70 of about 3,482,455 (367)
Biochemical Properties of Tissue-Engineered Cartilage [PDF]
Journal of Craniofacial Surgery, 2014 Microtia is treated with rib cartilage sculpting and staged procedures; though aesthetically pleasing, these constructs lack native ear flexibility. Tissue-engineered (TE) elastic cartilage may bridge this gap; however, TE cartilage implants lead to hypertrophic changes with calcification and loss of flexibility.
John A. van Aalst +6 more
openaire +2 more sources
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Combination of biochemical and mechanical cues for tendon tissue engineering
Journal of Cellular and Molecular Medicine, 2017 Tendinopathies negatively affect the life quality of millions of people in occupational and athletic settings, as well as the general population.
Stefano Testa +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Algorithmic Self-Assembly of DNA: Theoretical Motivations and 2D Assembly Experiments [PDF]
, 2000 Biology makes things far smaller and more complex than anything produced by human engineering. The biotechnology revolution has for the first time given us the tools necessary to consider engineering on the molecular level.
Winfree, Erik
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Systems Biology Graphical Notation: Process Description language Level 1 [PDF]
, 2009 Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society would not have evolved at the same pace.
Anatoly Sorokin +4 more
core +2 more sources
Pitfalls in Early Bioprocess Development Using Shake Flask Cultivations
Engineering in Life SciencesFor about 100 years, the shake flask has been established for biotechnological cultivations as one of the most important cultivation systems in early process development.
Gesa Brauneck +7 more
doaj +1 more source
Nano Convergence, 2023 Natural killer (NK) cells have clinical advantages in adoptive cell therapy owing to their inherent anticancer efficacy and their ability to identify and eliminate malignant tumors. However, insufficient cancer-targeting ligands on NK cell surfaces often
Chae Eun Lee +7 more
doaj +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
システム生物学のための統合解析シミュレータ WinBEST-KIT の開発 [PDF]
, 2018 Previously, I developed the biochemical reaction simulator called WinBEST-KIT (Biochemical Engineering System analyzing Tool-KIT, which runs under Microsoft Windows) for analyzing complicated biochemical reaction systems such as metabolic pathways ...
Sekiguchi, Tatsuya +2 more
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