Results 61 to 70 of about 532,110 (332)

EC-BLAST: a tool to automatically search and compare enzyme reactions. [PDF]

, 2014
We present EC-BLAST (http://www.ebi.ac.uk/thornton-srv/software/rbl/), an algorithm and Web tool for quantitative similarity searches between enzyme reactions at three levels: bond change, reaction center and reaction structure similarity.
A Dalby, A Theocharidis, AL Cuff, C Jochum, C Steinbeck, DARSD Latino, F Mu, Gemma L Holliday, I Ugi, J Lees, J-L Faulon, Janet M Thornton, K Tipton, L Chen, M Kanehisa, M Kotera, M Leber, Nicholas Furnham, NM O'Boyle, NM O'Boyle, Q-Y Zhang, RHS Thompson, RS Cahn, S Heller, SA Rahman, SA Rahman, Sergio Martinez Cuesta, Syed Asad Rahman, T Sing, V Egelhofer, V Prelog, WL Chen, Y Yamanishi   +32 more
core   +3 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels [PDF]

, 2020
Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly ...
Hoey, David A., Parmentier, Laurens, Riffault, Mathieu   +2 more
core   +1 more source

Development of predictive model for the fixed-bed column reactor

Applied Water Science, 2023
The present study aims at development of a mathematical model for the fixed-bed column adsorption that relates the reactor parameters with the breakthrough curve. Effects of operating parameters like bed height, flow rate, initial adsorbate concentration
Jyoti Singh, Santhosh Kumar Kumaresan, Sarvanshi Swaroop, Vishal Mishra   +3 more
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Molecular Interactions. On the Ambiguity of Ordinary Statements in Biomedical Literature [PDF]

, 2009
Statements about the behavior of biochemical entities (e.g., about the interaction between two proteins) abound in the literature on molecular biology and are increasingly becoming the targets of information extraction and text mining ...
Jansen, Ludger, Schulz, Stefan
core  

Blind source separation methods for deconvolution of complex signals in cancer biology

, 2013
Two blind source separation methods (Independent Component Analysis and Non-negative Matrix Factorization), developed initially for signal processing in engineering, found recently a number of applications in analysis of large-scale data in molecular ...
Kairov, Ulykbek, Karpenyuk, Tatiana, Ramanculov, Erlan, Zinovyev, Andrei   +3 more
core   +1 more source

Routes to industrial scalability to maximise investment in engineering biology in the UK—A bioplastics small and medium‐sized enterprise perspective

Engineering Biology
Focus on engineering biology is at the forefront of the UK government's objectives, being one of their five critical technologies (the others being quantum technologies, artifical intelligence, semiconductors, and future telecommunications), with a ...
Amy Switzer, Laima Šusta, Paul Mines
doaj   +1 more source

Effect of aprotic solvent on characteristics of Al2O3 ceramic hollow fiber substrates prepared by phase inversion for hydrogen permeation applications

Journal of Asian Ceramic Societies, 2022
The phase inversion procedure was used to prepare Al2O3 ceramic hollow fiber substrates (AlCHFS) utilizing the dimethyl sulfoxide (DMSO), N,N-dimethylacetamide (DMAC), and 1-methyl-2-pyrrolidone (NMP) aprotic solvents.
Edoardo Magnone, Seung Hwan Lee, Min Chang Shin, Xuelong Zhuang, Jae Yeon Hwang, Jeong In Lee, Jung Hoon Park   +6 more
doaj   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source