Results 51 to 60 of about 240,710 (295)
Water-in-water (w/w) emulsions can mimic biological environments, and their stability is ensured by adding nanoparticles capable of adsorbing at liquid-liquid interfaces.
Marcelo da Silva Pedro +7 more
doaj +1 more source
Alternative splicing, polyadenylation, and chemical modifications of RNA generate astonishing complexity within eukaryotic transcriptomes. The last decade has brought numerous advances in sequencing technologies that allow biologists to investigate these
Sushant Bangru, Auinash Kalsotra
doaj +1 more source
Steady state is an essential concept in reaction networks. Its stability reflects fundamental characteristics of several biological phenomena such as cellular signal transduction and gene expression.
Hasegawa, Yoshihiko, Van Vu, Tan
core +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Bifurcation of Localized Disturbances in a Model Biochemical Reaction [PDF]
Asymptotic solutions are presented to the nonlinear parabolic reaction-diffusion equations describing a model biochemical reaction proposed by I. Prigogine.
Boa, James A., Cohen, Donald S.
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The modular biochemical reaction network structure of cellular translation
Translation is an essential attribute of all living cells. At the heart of cellular operation, it is a chemical information decoding process that begins with an input string of nucleotides and ends with the synthesis of a specific output string of ...
Bruno Cuevas-Zuviría +3 more
doaj +1 more source
Slowly modulated oscillations in nonlinear diffusion processes [PDF]
It is shown here that certain systems of nonlinear (parabolic) reaction-diffusion equations have solutions which are approximated by oscillatory functions in the form R(ξ - cτ)P(t^*) where P(t^*) represents a sinusoidal oscillation on a fast time scale t*
Cohen, Donald S. +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

