Results 61 to 70 of about 1,010,901 (298)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Metabolic Analysis Using HR-MAS in Prostate Tissue to Predict Biochemical Recurrence in Prostate Cancer

Urology Research and Practice
Objective: In this study, nuclear magnetic resonance (NMR) spectroscopy was used in prostate tissue to gather novel data on biomarkers that could predict biochemical recurrence in prostate cancer.
Jorge Panach-Navarrete, Vannina González-Marrachelli, José Manuel Morales-Tatay, Francisco García-Morata, María Ángeles Sales-Maicas, Daniel Monleón-Salvado, José María Martínez Jabaloyas   +6 more
doaj   +1 more source

Contrast-enhanced transrectal ultrasound can reduce collection of unnecessary biopsies when diagnosing prostate cancer and is predictive of biochemical recurrence following a radical prostatectomy in patients with localized prostate cancer

BMC Urology, 2020
Background To investigate the value of using contrast-enhanced transrectal ultrasound (CETRUS) to reduce unnecessary collection of biopsies during prostate cancer diagnosis and its utility in predicting biochemical recurrence in patients with localized ...
Hong-wei Zhao, Jian Li, Jia-Zheng Cao, Juan Lin, Zhu Wang, Jian-yao Lv, Jin-huan Wei, Zhen-hua Chen, Hao-hua Yao, Yi-hui Pan, Zhen-li Gao, Jun-hang Luo, Wei Chen, Lei Shi, Yong Fang   +14 more
doaj   +1 more source

Impact TMPRSS2–ERG Molecular Subtype on Prostate Cancer Recurrence

Life, 2021
Currently, seven molecular subtypes of prostate cancer (PCa) are known, the most common of which being the subtype characterized by the presence of the TMPRSS2–ERG fusion transcript.
Anastasiya A. Kobelyatskaya, Elena A. Pudova, Anastasiya V. Snezhkina, Maria S. Fedorova, Vladislav S. Pavlov, Zulfiya G. Guvatova, Maria V. Savvateeva, Nataliya V. Melnikova, Alexey A. Dmitriev, Dmitry Y. Trofimov, Gennady T. Sukhikh, Kirill M. Nyushko, Boris Y. Alekseev, Sergey V. Razin, George S. Krasnov, Anna V. Kudryavtseva   +15 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A novel miRNA-based predictive model for biochemical failure following post-prostatectomy salvage radiation therapy. [PDF]

PLoS ONE, 2015
To develop a microRNA (miRNA)-based predictive model for prostate cancer patients of 1) time to biochemical recurrence after radical prostatectomy and 2) biochemical recurrence after salvage radiation therapy following documented biochemical disease ...
Erica Hlavin Bell, Simon Kirste, Jessica L Fleming, Petra Stegmaier, Vanessa Drendel, Xiaokui Mo, Stella Ling, Denise Fabian, Isabel Manring, Cordula A Jilg, Wolfgang Schultze-Seemann, Maureen McNulty, Debra L Zynger, Douglas Martin, Julia White, Martin Werner, Anca L Grosu, Arnab Chakravarti   +17 more
doaj   +1 more source

Double trouble: does co-morbid chronic somatic illness increase risk for recurrence in depression? A systematic review [PDF]

, 2013
Objective: To perform a systematic review, and if possible a meta-analysis, to establish whether depressed patients with comorbid chronic somatic illnesses are a high risk "double trouble" group for depressive recurrence.
Huibert Burger, Pijnenborg, Gerdina H. M., Gerdina H. M. Pijnenborg, Burger, H, Steven D. Hollon, Gemma D. Kok, Burger, Huibert, Cuijpers, Pim, Bockting, Claudi L H, Hannig, W., Wiebke Hannig, Hollon, S.D., Bockting, Claudi L. H., Pim Cuijpers, Steven D Hollon, Pijnenborg, G.H.M., Kok, Gemma D, Kok, Gemma D., Hollon, Steven D., Claudi L H Bockting, Burger, Huibert; id_orcid, Bockting, Claudi, Claudi L. H. Bockting, Gerdina H M Pijnenborg, Kok, G.D., Bockting, C.L.H., Hollon, Steven D, Kok, G., Pijnenborg, Gerdina H M, Cuijpers, P., Hannig, Wiebke, Burger, H., Gemma D Kok   +32 more
core   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Biochemical recurrence rates are similar for pT2-positive surgical margins and pT3a

International Brazilian Journal of Urology, 2014
Objective Histological details of positive surgical margins in radical prostatectomy specimens have been related to outcome after surgery in rare studies recently published.
Katia R. M. Leite, Carolina Hartmann, Sabrina T. Reis, Nayara Viana, Marcos F. Dall?Oglio, Alexandre C. Sant?Anna, Adriano Nesrallah, Luciano Nesrallah, Alberto A. Antunes, Luiz H. Camara-Lopes, Miguel Srougi   +10 more
doaj   +1 more source

recurrence

, 2012
Time to recurrence or censure for 136 patients. VSCode column contains a recurrence flag (1=recurrence, 0=no recurrence). Years column is the time to recurrence or censuring (ie., end of observation without a recurrence)
Sinicropi, Dominick, Stephans, James, Dei Rossi, Andrew, Qu, Kunbin, Collin, Francois, Crager, Michael, John Morlan (151332), Pelham, Robert J., Esteban, Jose M., Liu, Mei-Lan, Zheng, Christina, Baker, Joffre, Joffre Baker (20987), Dominick Sinicropi (151288), Jennie Jeong (151310), Mylan Pho (20986), James Stephans (151329), Mena, Raul, Francois Collin (18691), Ranjana Ambannavar (151316), Andrew Dei Rossi (151305), Mei-Lan Liu (151299), Jose M. Esteban (3276027), Kunbin Qu (2660), Aaron Scott (151313), Jeong, Jennie, Scott, Aaron, Christina Zheng (151321), Pho, Mylan, Morlan, John, Michael Crager (151294), Ambannavar, Ranjana, Raul Mena (151324), Robert J. Pelham (131925)   +33 more
core   +1 more source