Results 41 to 50 of about 69,923 (265)
Acta Biochimica Polonica, 2022 This article presents the history of the establishment and development of the Institute of Molecular Biology at Jagiellonian University, describes the reasons for the transformation of the Institute into the Faculty of Biochemistry, Biophysics and Biotechnology, and provides information on the current scientific and teaching potential of the Faculty ...
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis
Nature Communications, 2021 Borosins are ribosomally encoded and posttranslationally modified peptide (RiPP) natural products featuring amide-backbone α-N-methylation. Here, the authors report the discovery and characterization of type IV borosin ‘split’ pathways encoding distinct,
Fredarla S. Miller +6 more
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Predicting thresholds for population replacement gene drives
BMC BiologyBackground Threshold-dependent gene drives (TDGDs) could be used to spread desirable traits through a population, and are likely to be less invasive and easier to control than threshold-independent gene drives. Engineered Genetic Incompatibility (EGI) is
Anna Janzen +4 more
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Nature Communications, 2016 The APOBEC family of enzymes are cytidine deaminases with APOBEC3A and APOBEC3B thought to contribute to DNA damage signatures detected in cancer genomes.
Gabriel J. Starrett +11 more
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A Rabbit Monoclonal Antibody against the Antiviral and Cancer Genomic DNA Mutating Enzyme APOBEC3B
Antibodies, 2019 The DNA cytosine deaminase APOBEC3B (A3B) is normally an antiviral factor in the innate immune response. However, A3B has been implicated in cancer mutagenesis, particularly in solid tumors of the bladder, breast, cervix, head/neck, and lung.
William L. Brown +10 more
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Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Analysis of the colombian scientific production in chemistry. Wokdatabase(2001-2012)
Logos Ciencia & Tecnología, 2014 An exploratory analysis is presented through somes cientometric indicators of production of articles in thearea of chemistry with Colombian author institutional affiliation,reported in the Web of Knowledge(2001 - 2012).
Nubia Yaneth Gómez Velasco +3 more
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