Results 51 to 60 of about 143,906 (309)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Schematic relationship between biochemistry, genetics and molecular biology

, 2016
The image's scheme show the connection between biochemistry, molecular biology and genetics, also explaining the relationships of functions, genes and proteinsComponente Curricular::Ensino Médio ...
Desconhecido
core   +1 more source

NIKOLAI KONSTANTINOVICH KOL’TSOV, THE AUTHOR OF THE TEMPLATE-DIRECTED SYNTHESIS CONCEPT AND FOUNDER OF EXPERIMENTAL BIOLOGY IN RUSSIA

Вавиловский журнал генетики и селекции, 2014
Nikolai K. Kol’tsov (1872–1940) went on his scientific way from comparative anatomy of vertebrates to experimental cytology and then to genetics and molecular biology. He discovered the cytoskeleton.
N. N. Yurchenko, O. V. Trapezov, I. K. Zakharov   +2 more
doaj  

Whole exon screening of SLC2A4 gene and the association of rs5435 with type 2 diabetes in a Bangladeshi case-control study

Journal of Genetic Engineering and Biotechnology
Type 2 diabetes (T2D) is a multifaceted disease influenced by both genetic and environmental factors, posing significant global health challenges. Polymorphisms in the SLC2A4 gene encoding the glucose transporter 4 (GLUT4), have been linked to insulin ...
Mohammad Mamunur Rashid, Mohammad Sayem, Maisha Adiba, Abdullah Al Saba, A.H.M. Nurun Nabi, Tahirah Yasmin   +5 more
doaj   +1 more source

Evaluating the seroprevalence of SARS-CoV-2 IgG in five different districts of Bangladesh. A seroepidemiological study

Journal of Infection and Public Health, 2023
Background: We aimed to measure the seroprevalences and levels of anti-SARS-CoV-2 IgG in children, unvaccinated and vaccinated adults in five districts of Bangladesh and thus, investigate the association of seroprevalence and anti-SARS-CoV-2 IgG level ...
Abdullah Al Saba, Mohammad Sayem, Razoan Al Rimon, Mousumi Sanyal, Sajib Chakraborty, Md Arifur Rahman, Md Mizanur Rahman, A.H.M. Nurun Nabi   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A Comparative Meta‐Analysis on the Association of lncRNAs MALAT1, HOTAIR, and AFAP1‐AS1 With the Risk of Developing Lymph Node Metastasis in Lung Cancer

Cancer Reports
Background Numerous studies have demonstrated the significance of long noncoding RNA (lncRNA) in the development of cancer metastasis. The expression levels of many lncRNAs are elevated in metastatic lung cancer patients compared to non‐metastatic lung ...
Anha Tasnim, Afra Anjum Sumaiya, Abdullah Al Noman, Anika Tahsin, Abdullah Al Saba, Rubaiat Ahmed, Tahirah Yasmin, A. H. M. Nurun Nabi   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Research advances of Galliformes since 1990 and future prospects

Avian Research, 2018
Background Galliformes are widely distributed throughout the world and economically important to humans as domesticated animals or gamebirds. They are at a unique position for advancing knowledge and techniques of wildlife conservation as the barometer ...
Shan Tian, Jiliang Xu, Jianqiang Li, Zhengwang Zhang, Yong Wang   +4 more
doaj   +1 more source