Results 101 to 110 of about 368,095 (294)

Sustainability and groundwater in the context of Water-Energy-Food Nexus: a review of the literature

open access: yesDerbyana
The sustainability of groundwater is contingent upon the Water-Energy-Food Nexus. In this context, the article aimed to analyze the state of the art in this field by using the Scopus database and the following keywords: “Sustainability”, “Nexus”, and ...
Sandra Milena Vélez Echeverry   +2 more
doaj   +1 more source

Influential cited references in FEMS Microbiology Letters: lessons from Reference Publication Year Spectroscopy (RPYS)

open access: yes, 2019
The journal FEMS Microbiology Letters covers all aspects of microbiology including virology. On which scientific shoulders do the papers published in this journal stand? Which are the classic papers used by the authors?
Bauer, J., Bornmann, L., Haunschild, R.
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Are textbook references to Darwin close to extinction? [PDF]

open access: yes, 2008
The textbooks used to teach GCE A-level biology 30 years ago tended to concentrate on traditional zoology and botany, with just a passing reference to evolution. As biology established itself as a new discipline, books (and syllabuses) began to take an
Rees, PA
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Targeting ubiquitin-specific protease 14 reduces metastatic potential and metabolic activity in cervical cancer via direct modulation of monocarboxylate transporter-4

open access: yesJournal of Translational Medicine
Background Cervical cancer (CC) remains a major health burden in low- and middle-income countries, where HPV vaccination coverage is suboptimal. Ubiquitin-specific peptidase 14 (USP14), a proteasome-associated deubiquitinase, has emerged as a potential ...
Ravi Chauhan   +20 more
doaj   +1 more source

Economic Evaluation of Multiple-Pharmacogenes Testing for the Prevention of Adverse Drug Reactions in People Living with HIV

open access: yesClinicoEconomics and Outcomes Research, 2022
Saowalak Turongkaravee,1 Naiyana Praditsitthikorn,2 Thundon Ngamprasertchai,3 Jiraphun Jittikoon,4 Surakameth Mahasirimongkol,5 Chonlaphat Sukasem,6– 9 Wanvisa Udomsinprasert,4 Olivia Wu,10 Usa Chaikledkaew11,12 1Social, Economic and Administrative ...
Turongkaravee S   +8 more
doaj  

Molecular Markers Used to Reveal Genetic Diversity and Phylogenetic Relationships in Crop Plants

open access: yesOBM Genetics
Genetic diversity allows plants to adapt to changing environmental conditions to survive and increases their ability to respond to yield, production, pests and diseases.
Özlem Özbek
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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