Results 81 to 90 of about 133,000 (268)

Introductory Biology

, 2005
The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology.
Gardel, Claudette L., Sive, Hazel L., Jacks, Tyler   +2 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

It’s all foreign to me: learning through the language of genetics and molecular biology

, 2012
Molecular Biology and Genetics are taught to undergraduate students at the second and third year level of their University of Canberra degrees. The assumption is, particularly for the third year students who have passed previous units/subjects in ...
Zhang, Felicia, Lidbury, Brett A.
core  

Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers [PDF]

, 2011
Metabolomic profiling and the integration of whole-genome genetic association data has proven to be a powerful tool to comprehensively explore gene regulatory networks and to investigate the effects of genetic variation at the molecular level.
Polonikov, Alexey, Wichmann, Heinz-Erich, Fabian J. Theis, Stephan Weidinger, Wichmann Heinz Erich, Gieger, C., Ried, Janina S., Christian Gieger, Krumsiek, J., Karsten Suhre, Prehn, C., Kirstin Mittelstrass, Heinz Erich Wichmann, Polonikov, A., Weidinger, S., Alexey Polonikov, Werner Roemisch-Margl, Yu Zhonghao, Theis, F.J., Wang-Sattler, R., Jan Krumsiek, Ried Janina S., Yu, Z., Gieger Christian, Mittelstrass, Kirstin, Wichmann, H.-E., Polonikov Alexey, Illig, T., Fabian J Theis, Peters, Annette, Illig Thomas, Mittelstrass Kirstin, Zhonghao Yu, Theis, Fabian J., Peters Annette, Kronenberg Florian, Florian Kronenberg, Jerzy Adamski, Annette Peters, Wang-Sattler, Rui, Krumsiek, Jan, Theis Fabian J., Peters, A., Krumsiek Jan, Illig, Thomas, Roemisch-Margl Werner, Wang-Sattler Rui, Meitinger, Thomas, Adamski, Jerzy, Ried, J.S., Cornelia Prehn, Thomas Illig, Römisch-Margl, W., Suhre Karsten, Gieger, Christian, Weidinger, Stephan, Weidinger Stephan, Suhre, K., Roemisch-Margl, Werner, Kronenberg, Florian, Yu, Zhonghao, Adamski Jerzy, Thomas Meitinger, Meitinger, T., Prehn, Cornelia, Rui Wang-Sattler, Kronenberg, F., Janina S. Ried, Prehn Cornelia, Adamski, J., Mittelstraß, K., Suhre, Karsten, Janina S Ried, Meitinger Thomas   +73 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Mechanisms of antioxidant defense in the state of post-hypoxia in Phrynops geoffroanus (Testudines: Chelidae)

, 2016
Phrynops geoffroanus (Testudines: Chelidae), comprises a group of reptiles that are tolerant to variations in environmental oxygen availability. Due to this characteristic, they are considered an excellent model for studies that aim the understanding of ...
Costa, N. R. A. [UNESP], Venancio, L. P. R. [UNESP], Bonini-Domingos, C. R. [UNESP]   +2 more
core   +1 more source

Collecting, archiving and processing DNA from wildlife samples using FTA® databasing paper [PDF]

, 2004
Background Methods involving the analysis of nucleic acids have become widespread in the fields of traditional biology and ecology, however the storage and transport of samples collected in the field to the laboratory in such a manner to allow ...
LA Burgoyne, Smith, L M, LM Smith, Burgoyne, Leigh Alexander   +3 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Introductory Biology

, 2019
The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology.
Jacks, Tyler, Sive, Hazel
core  

Mutations, Differential Gene Expression, and Chimeric Transcripts in Esophageal Squamous Cell Carcinoma Show High Heterogeneity

Translational Oncology, 2018
Esophageal squamous cell carcinoma (ESCC) is a frequent and lethal neoplasia. As recent advances in targeted therapy have not improved ESCC prognosis, characterization of molecular alterations associated to this tumor is of foremost relevance.
Paulo Thiago de Souza-Santos, Sheila Coelho Soares Lima, Pedro Nicolau-Neto, Mariana Boroni, Nathalia Meireles Da Costa, Lilian Brewer, Albert Nobre Menezes, Carolina Furtado, Miguel Angelo Martins Moreira, Hector N. Seuanez, Tatiana de Almeida Simão, Luis Felipe Ribeiro Pinto   +11 more
doaj   +1 more source