Results 61 to 70 of about 133,000 (268)

Population Genetic Approaches to Speciation of Wild Tomatoes with Special Reference to Solanum habrochaites and S. arcanum [PDF]

, 2009
This thesis entails the results of three research projects. These have focused on the influence of diversity, demography and structure in the divergence (i.e. the speciation process) of four wild tomato species.
Merino Méndez, Carlos Gonzalo
core  

A bibliometric study on Sordariales fungi covering genetic diversity, ecological interactions and biotechnological applications [PDF]

Global Journal of Environmental Science and Management
The kingdom fungi, with its vast diversity and applications, is crucial in maintaining ecosystem balance and supporting industries like food production and environmental protection.
N.F. Wulandari, A.R. Syam, L. Alhamd, B. Gunadi, Yosmaniar ,, E. Widjaja, B.N. Utomo, S. Wahyuwardani, R. Widiastuti, T. Kadarini, D. Safar   +10 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism

Neoplasia: An International Journal for Oncology Research, 2019
SIRT3 is a major mitochondrial deacetylase, which regulates various metabolic pathways by deacetylation; however, the effect of SIRT3 on proline metabolism is not reported.
Shuaiyi Chen, Xin Yang, Miao Yu, Zhe Wang, Boya Liu, Minghui Liu, Lu Liu, Mengmeng Ren, Hao Qi, Junhua Zou, Ivana Vucenik, Wei-Guo Zhu, Jianyuan Luo   +12 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A systems approach to analyze transcription factors in mammalian cells

, 2011
Transcription factors (TFs) play a central role in the development of multicellular organisms. The sequential actions of critical TFs direct cells to adopt defined differentiation pathways leading to functional, fully differentiated tissues.
Wilfred van IJcken, Rijkers, E, Andrieu-Soler, C, Frank Grosveld, Thongjuea, S, Jeroen Demmers, Soler, Eric, Boer, Ernie, Eric Soler, Jan Christian Bryne, Demmers, Jeroen, Ernie de Boer, Bryne, JC, van Ijcken, Wilfred, Grosveld, Frank, Erikjan Rijkers, Supat Thongjuea, Charlotte Andrieu-Soler, van Ijcken, Wilfred; id_orcid   +18 more
core   +1 more source

Crystal structures of trypanosoma brucei oligopeptidase B broaden the paradigm of catalytic regulation in prolyl oligopeptidase family enzymes [PDF]

, 2013
Oligopeptidase B cleaves after basic amino acids in peptides up to 30 residues. As a virulence factor in bacteria and trypanosomatid pathogens that is absent in higher eukaryotes, this is a promising drug target.
Rory E Morty, Canning Peter, Rea, Dean, Dean Rea (483664), Morty Rory E., Morty, Rory E., Dean Rea, Vilmos Fülöp, Rory E. Morty (341515), Canning, Peter, Fülöp, Vilmos, Peter Canning, Peter Canning (483663), Vilmos Fülöp (483665), Rea Dean, Fülöp Vilmos   +15 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Clinical characteristics and predictors of gangrene in patients with systemic sclerosis and digital ulcers in the Digital Ulcer Outcome Registry: a prospective, observational cohort [PDF]

, 2016
Disease Activity; Outcomes research; Systemic Sclerosis; Immunology and Allergy; Rheumatology; Immunology; Biochemistry, Genetics and Molecular Biology ...
Denton, Christopher P., Rosenberg, Daniel, Denton, CP, Allanore, Yannick, Schwierin, Barbara, DUO Investigators, ., Schwierin, B, Cornelisse, Peter, Krieg, Thomas, Denton, Christopher P, Cornelisse, P, Matucci-Cerinic, M, Matucci-Cerinic, Marco, Krieg, T, Rosenberg, D, Krieg, Thomas M., Allanore, Y   +16 more
core   +1 more source

Gene expression patterns of sulfur starvation in Synechocystis sp. PCC 6803

BMC Genomics, 2008
Background The unicellular cyanobacterium Synechocystis sp. PCC 6803 is a model microbe for studying biochemistry, genetics and molecular biology of photobiological processes.
Pendse Ninad D, Zhang Zhigang, Phillips Katherine N, Cotner James B, Khodursky Arkady   +4 more
doaj   +1 more source