Results 111 to 120 of about 3,029,318 (218)
The Genetic Code as a Chronicle of Early Events in the Origin of Life [PDF]
arXiv, 1998 Molecular evidence regarding the genetic code has been examined and the findings on the nature of the early events responsible for the amino acid distribution in the code are reported.
arxiv
Predicting genetic interactions from Boolean models of biological networks [PDF]
arXiv, 2015 Genetic interaction can be defined as a deviation of the phenotypic quantitative effect of a double gene mutation from the effect predicted from single mutations using a simple (e.g., multiplicative or linear additive) statistical model. Experimentally characterized genetic interaction networks in model organisms provide important insights into ...
arxiv
SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism
Neoplasia: An International Journal for Oncology Research, 2019 SIRT3 is a major mitochondrial deacetylase, which regulates various metabolic pathways by deacetylation; however, the effect of SIRT3 on proline metabolism is not reported.
Shuaiyi Chen +12 more
doaj
Clinical molecular genetics in the UK c.1975-c.2000 [PDF]
, 2014 seminar transcriptChaired by Professor Martin Bobrow and introduced by Professor Bob Williamson, this Witness Seminar included geneticists from a broad range of research and clinical specialities.
Jones, EM, Tansey, EM
core
Motile cilia genetics and cell biology: big results from little mice
Cellular and Molecular Life Sciences, 2020 Lance Lee, L. Ostrowski
semanticscholar +1 more source
Worldwide Research Trends on Wheat and Barley: A Bibliometric Comparative Analysis [PDF]
, 2019 Grain cereals such as wheat, barley, rice, and maize are the nutritional basis of humans and animals worldwide. Thus, these crop plants are essential in terms of global food security.
Benavente Barzana, María Elena +3 more
core +1 more source
Mapping Evolution of Molecules Across Biochemistry with Assembly Theory [PDF]
arXivEvolution is often understood through genetic mutations driving changes in an organism's fitness, but there is potential to extend this understanding beyond the genetic code. We propose that natural products - complex molecules central to Earth's biochemistry can be used to uncover evolutionary mechanisms beyond genes. By applying Assembly Theory (AT),
arxiv
Neoplasia: An International Journal for Oncology Research, 2019 Chromosomal aneuploidy is a defining feature of epithelial cancers. The pattern of aneuploidies is cancer-type specific. For instance, the gain of chromosome 13 occurs almost exclusively in colorectal cancer.
Darawalee Wangsa +16 more
doaj
A genome-scale deep learning model to predict gene expression changes of genetic perturbations from multiplex biological networks [PDF]
arXivSystematic characterization of biological effects to genetic perturbation is essential to the application of molecular biology and biomedicine. However, the experimental exhaustion of genetic perturbations on the genome-wide scale is challenging. Here, we show that TranscriptionNet, a deep learning model that integrates multiple biological networks to ...
arxiv
Understanding nature's choice of genetic languages [PDF]
BioSystems 250 (2025), Article 105428All living organisms use the same genetic languages in their molecular biology machinery. They can be understood as the optimal solutions to the replication tasks involving DNA and proteins. These solutions perfectly fit the pattern predicted by Grover's algorithm, which is more efficient than the best Boolean search algorithm (i.e. binary tree search)
arxiv