Fast-mode elimination in stochastic metapopulation models [PDF]
Phys. Rev. E 89, 032141 (2014), 2014 We investigate the stochastic dynamics of entities which are confined to a set of islands, between which they migrate. They are assumed to be one of two types, and in addition to migration, they also reproduce and die. Systems which fall into this class are common in biology and social science, occurring in ecology, population genetics, epidemiology ...
arxiv +1 more source
Is Coronavirus-Related Research Becoming More Interdisciplinary? A Perspective of Co-occurrence Analysis and Diversity Measure of Scientific Articles [PDF]
, 2021 The outbreak of coronavirus disease 2019 (COVID-19) has had a significant repercussion on the health, economy, politics and environment, making coronavirus-related issues more complicated and difficult to solve adequately by relying on a single field. Interdisciplinary research can provide an effective solution to complex issues in the related field of
arxiv +1 more source
Expression systems for industrial Gram-positive bacteria with low guanine and cytosine content [PDF]
, 1997 Recent years have seen an increase in the development of gene expression systems for industrial Gram-positive bacteria with low guanine and cytosine content that belong to the genera Bacillus, Clostridium, Lactococcus, Lactobacillus, Staphylococcus and ...
Kleerebezem, Michiel, +2 more
core +2 more sources
CAR-T-Cell Therapy in Multiple Myeloma: B-Cell Maturation Antigen (BCMA) and Beyond
Vaccines, 2023 Significant progress has been achieved in the realm of therapeutic interventions for multiple myeloma (MM), leading to transformative shifts in its clinical management.
Abhinava K. Mishra +19 more
doaj +1 more source
Specificity and stability in topology of protein networks [PDF]
Science, 296, 910-913 (2002), 2002 Molecular networks guide the biochemistry of a living cell on multiple levels: its metabolic and signalling pathways are shaped by the network of interacting proteins, whose production, in turn, is controlled by the genetic regulatory network. To address topological properties of these two networks we quantify correlations between connectivities of ...
arxiv +1 more source
Beyond Low Earth Orbit: Biological Research, Artificial Intelligence, and Self-Driving Labs [PDF]
arXiv, 2021 Space biology research aims to understand fundamental effects of spaceflight on organisms, develop foundational knowledge to support deep space exploration, and ultimately bioengineer spacecraft and habitats to stabilize the ecosystem of plants, crops, microbes, animals, and humans for sustained multi-planetary life.
arxiv
TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. [PDF]
, 2015 The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family.
Corbett, Kevin D +5 more
core +2 more sources
Towards Developmental Models of Psychiatric Disorders in Zebrafish
Frontiers in Neural Circuits, 2013 Psychiatric disorders are a diverse set of diseases that affect all aspects of mental function including social interaction, thinking, feeling and mood.
William Howard James Norton
doaj +1 more source
Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics. [PDF]
, 2015 Microtubule dynamics and polarity stem from the polymerization of αβ-tubulin heterodimers. Five conserved tubulin cofactors/chaperones and the Arl2 GTPase regulate α- and β-tubulin assembly into heterodimers and maintain the soluble tubulin pool in the ...
Al-Bassam, Jawdat +7 more
core +2 more sources
T2D-Db: An integrated platform to study the molecular basis of Type 2 diabetes
BMC Genomics, 2008 Background Type 2 Diabetes Mellitus (T2DM) is a non insulin dependent, complex trait disease that develops due to genetic predisposition and environmental factors.
Sriram S +7 more
doaj +1 more source