Results 101 to 110 of about 1,957,522 (351)

Stochastic single-particle based simulations of cellular signaling embedded into computational models of cellular morphology [PDF]

open access: yesarXiv, 2020
Cells exhibit a wide variety of different shapes. This diversity poses a challenge for computational approaches that attempt to shed light on the role cell geometry plays in regulating cell physiology and behavior. The simulation platform Simmune is capable of embedding the computational representation of signaling pathways into realistic models of ...
arxiv  

Thiol biochemistry of prokaryotes [PDF]

open access: yes
The present studies have shown that GSH metabolism arose in the purple bacteria and cyanobacteria where it functions to protect against oxygen toxicity.
Fahey, Robert C.
core   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Retracted: Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum

open access: yesBiochemistry Research International, 2022
Biochemistry Research International
doaj   +1 more source

The enzymatic determination of glucose in carbonated beverages: a useful tool for the undergraduate students to learn the basis of enzymatic analysis and the comparison of two analytical methods [PDF]

open access: yes, 2017
The importance of enzymatic analysis in biochemistry, clinical chemistry and food chemistry is undoubted. The course "Applied Biochemistry" in our Faculty is aimed to undergraduate students of Chemistry and Biochemistry.
Blanco-Lopez, Angel   +4 more
core  

Biochemistry of the menopause [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2017
The life of a human female is characterized from teenage years by monthly menstruation which ceases (the menopause) typically between the age of 40 and 60 years. The potential for reproduction declines and ceases as the ovaries become depleted of follicles. A transition period in mid-life, for 2 to 10 years, when menstruation is less regular is called
openaire   +3 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Precision and trueness verification study of an Atellica system

open access: yesAdvances in Laboratory Medicine, 2020
Clinical laboratories should use only validated procedures. Precision is an important factor in the validation and verification of a new measurement procedure.
Vílchez Rodríguez Alberto   +4 more
doaj   +1 more source

A Unified Theory of Chemical Reactions [PDF]

open access: yesarXiv, 2014
We propose a new and general formalism for elementary chemical reactions where quantum electronic variables are used as reaction coordinates. This formalism is in principle applicable to all kinds of chemical reactions ionic or covalent. Our theory reveals the existence of an intermediate situation between ionic and covalent which may be almost ...
arxiv  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

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