Results 81 to 90 of about 2,109,968 (300)

Retracted: Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum

open access: yesBiochemistry Research International, 2022
Biochemistry Research International
doaj   +1 more source

Elevated Fecal pH Indicates a Profound Change in the Breastfed Infant Gut Microbiome Due to Reduction of Bifidobacterium over the Past Century

open access: yesmSphere, 2018
Historically, Bifidobacterium species were reported as abundant in the breastfed infant gut. However, recent studies in resource-rich countries show an increased abundance of taxa regarded as signatures of dysbiosis.
Bethany M. Henrick   +7 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Rapamycin and Chloroquine Modulate Insulin Resistance and Hepatic Steatosis in a High-Fat/High-Cholesterol Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease Mouse Model

open access: yesDiabetes, Metabolic Syndrome and Obesity
Qi Liu,1,* Qian Du,2,* Xiaolu Yuan,3 Ting Zhang,3 Jiajing Li,3 Jingyu Xu,4 Rui Xie2 1Department of Gastroenterology, Zhejiang Provincial People’s Hospital Bijie Hospital, Bijie, Guizhou, People’s Republic of China; 2Department of ...
Liu Q   +6 more
doaj  

Spontaneous chiral parity breaking by hydromagnetic buoyancy

open access: yes, 2011
Evidence for a parity-breaking nature of the magnetic buoyancy instability in a stably stratified gas is reported. In the absence of rotation, no helicity is produced, but the non-helical state is found to be unstable to small helical perturbations ...
Brandenburg, Axel   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Oxidative stress in dogs with cardiorenal syndrome caused by endocardiosis

open access: yesRUDN Journal of Agronomy and Animal Industries
Oxidative stress and decreased antioxidant defense were registered in dogs with endocardiosis. Complication of underlying pathology in the form of cardiorenal syndrome leads to aggravation of lipid peroxidation processes and causes further decrease in ...
Yuri A. Vatnikov   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Determining the Minimum Time Interval for Completely Eliminating the Carryover Effect of Dehydration in Heat-Stressed Goats: Insights from Physiochemical Mechanisms

open access: yesTropical Animal Science Journal
Heat stress, coupled with water deprivation, is widely acknowledged as one of the most potent stressors capable of impairing the production performance of small ruminants; therefore, comprehending and mitigating this stressor is of paramount importance.
E. M. Samara   +3 more
doaj   +1 more source

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