Results 81 to 90 of about 1,481,933 (313)

Department of Chemistry and Biochemistry Seminar Schedule 2007 Spring

, 2007
University of Minnesota Duluth. Department of Chemistry and Biochemistry. (2007). Department of Chemistry and Biochemistry Seminar Schedule 2007 Spring.
University of Minnesota Duluth. Department of Chemistry and Biochemistry
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Corosolic acid attenuates cardiac ischemia/reperfusion injury through the PHB2/PINK1/parkin/mitophagy pathway

iScience
Summary: Despite advances in treatment, myocardial infarction remains the leading cause of heart failure and death worldwide, and the restoration of coronary blood flow can also cause heart damage.
Jun Zhang, Yongjian Zhao, Lin Yan, Mingyue Tan, Yifeng Jin, Yunfei Yin, Lianhua Han, Xiao Ma, Yimin Li, Tianke Yang, Tingbo Jiang, Hongxia Li   +11 more
doaj   +1 more source

Department of Chemistry and Biochemistry Seminar Schedule 2010 Spring

, 2010
University of Minnesota Duluth. Department of Chemistry and Biochemistry. (2010). Department of Chemistry and Biochemistry Seminar Schedule 2010 Spring.
University of Minnesota Duluth. Department of Chemistry and Biochemistry
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Signal execution modes emerge in biochemical reaction networks calibrated to experimental data

iScience
Summary: Mathematical models of biomolecular networks are commonly used to study cellular processes; however, their usefulness to explain and predict dynamic behaviors is often questioned due to the unclear relationship between parameter uncertainty and ...
Oscar O. Ortega, Mustafa Ozen, Blake A. Wilson, James C. Pino, Michael W. Irvin, Geena V. Ildefonso, Shawn P. Garbett, Carlos F. Lopez   +7 more
doaj   +1 more source

Determination of Protein Concentration Using Bradford Microplate Protein Quantification Assay [PDF]

Disease and Diagnosis, 2015
Background: Bradford protein assay is popular due to its ease of performance and relative sensitivity. Many researchers and laboratories in Iran use standard assay of Bradford by cuvette.
Rouhollah Valipour Nouroozi, Moulood Valipour Noroozi, Masoumeh Ahmadizadeh   +2 more
doaj  

Department of Chemistry and Biochemistry Seminar Schedule 2006 Fall

, 2006
University of Minnesota Duluth. Department of Chemistry and Biochemistry. (2006). Department of Chemistry and Biochemistry Seminar Schedule 2006 Fall.
University of Minnesota Duluth. Department of Chemistry and Biochemistry
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Department of Chemistry and Biochemistry Seminar Schedule 2007 Fall

, 2007
University of Minnesota Duluth. Department of Chemistry and Biochemistry. (2007). Department of Chemistry and Biochemistry Seminar Schedule 2007 Fall.
University of Minnesota Duluth. Department of Chemistry and Biochemistry
core