Results 71 to 80 of about 1,481,933 (313)

Biochemistry Programs, Task Force, August 1983

open access: yes, 1983
University of Minnesota. Task Force on Biochemistry, 1983. (1983). Biochemistry Programs, Task Force, August 1983.
University of Minnesota. Task Force on Biochemistry, 1983
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Retracted: Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum

open access: yesBiochemistry Research International, 2022
Biochemistry Research International
doaj   +1 more source

Oxidative stress in dogs with cardiorenal syndrome caused by endocardiosis

open access: yesRUDN Journal of Agronomy and Animal Industries
Oxidative stress and decreased antioxidant defense were registered in dogs with endocardiosis. Complication of underlying pathology in the form of cardiorenal syndrome leads to aggravation of lipid peroxidation processes and causes further decrease in ...
Yuri A. Vatnikov   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Determining the Minimum Time Interval for Completely Eliminating the Carryover Effect of Dehydration in Heat-Stressed Goats: Insights from Physiochemical Mechanisms

open access: yesTropical Animal Science Journal
Heat stress, coupled with water deprivation, is widely acknowledged as one of the most potent stressors capable of impairing the production performance of small ruminants; therefore, comprehending and mitigating this stressor is of paramount importance.
E. M. Samara   +3 more
doaj   +1 more source

Digital portfolios for enhanced online learning in first-year Biochemistry

open access: yes, 2020
Student success and retention is of the utmost importance in higher education, particularly for large first year courses in STEM disciplines which involve understanding complex concepts and navigating a high level of content.
Love, Christopher
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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