Results 61 to 70 of about 427,584 (269)

Digital portfolios for enhanced online learning in first-year Biochemistry

open access: yes, 2020
Student success and retention is of the utmost importance in higher education, particularly for large first year courses in STEM disciplines which involve understanding complex concepts and navigating a high level of content.
Love, Christopher
core  

The multidisciplinary approach to biochemistry laboratory education

open access: yes, 2013
European Union's Life Long Learning Programmes and the Bologna Process describe new classifications. Related with these new classifications, our higher education system is being restructured under the name of National Qualification Frameworks ...
YÜKSEL, MERAL, HAKLAR, GONCAGÜL
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Radial variation in biochemical composition of the bovine caudal intervertebral disc

open access: yesJOR Spine, 2019
Bovine caudal discs have been widely used in spine research due to their increased availability, large size, and mechanical and biochemical properties that are comparable to healthy human discs. However, despite their extensive use, the radial variations
Semih E. Bezci   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Assessing the stability of uncentrifuged serum and plasma analytes at various post-collection intervals

open access: yesJournal of Laboratory Medicine
Our study aimed to assess the stability of 26 biochemistry analytes in serum or plasma samples separated from blood samples centrifuged at different time intervals after collection, simulating sample transport via despatch delivery systems.
Mokhsin Atiqah   +10 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Les acides gras des organes oppositifoliés de Vitis vinifera L. var. ugni blanc

open access: yesOENO One, 1975
On sait que les organes oppositifoliés de la Vigne, vrilles et inflorescences, sont assimilés à des rameaux modifiés. Diverses considérations, notamment l'étude des formes de transition entre ces organes, apportent des arguments en faveur de cette ...
Monique Cherrad   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

High rates of fuel consumption are not required by insulating motifs to suppress retroactivity in biochemical circuits

open access: yesEngineering Biology, 2017
Retroactivity arises when the coupling of a molecular network [inline-formula] to a downstream network [inline-formula] results in signal propagation back from [inline-formula] to [inline-formula].
Abhishek Deshpande, Thomas E. Ouldridge
doaj   +1 more source

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