Results 71 to 80 of about 1,957,522 (351)
FEBS Letters, EarlyView.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Subchronic Toxicity Evaluation of Ethanol Extract of Picria fel-terrae Lour. Leaf in Wistar Rats
Scientia Pharmaceutica, 2018 Picria fel-terrae extract has been investigated for its hepatoprotective activity. This current study was conducted to evaluate the subchronic toxic effect of Picria fel-terrae Lour. leaf extract. The subchronic toxicity of ethanol extract of P.
Urip Harahap +5 more
doaj +1 more source
Exact Parallelization of the Stochastic Simulation Algorithm for Scalable Simulation of Large Biochemical Networks [PDF]
arXiv, 2020 Comprehensive simulations of the entire biochemistry of cells have great potential to help physicians treat disease and help engineers design biological machines. But such simulations must model networks of millions of molecular species and reactions.
arxiv
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Les acides gras des organes oppositifoliés de Vitis vinifera L. var. ugni blanc
OENO One, 1975 On sait que les organes oppositifoliés de la Vigne, vrilles et inflorescences, sont assimilés à des rameaux modifiés. Diverses considérations, notamment l'étude des formes de transition entre ces organes, apportent des arguments en faveur de cette ...
Monique Cherrad +2 more
doaj +1 more source
Imaging biochemistry: applications to breast cancer. [PDF]
, 2001 The use of magnetic resonance spectroscopy (MRS) to investigate breast tumour biochemistry in vivo is reviewed. To this end, results obtained both from patients in vivo and from tumour extracts and model systems are discussed.
Leach, MO, Ronen, SM
core +1 more source
FEBS Letters, EarlyView.The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang +9 more
wiley +1 more source
Engineering Biology, 2017 Retroactivity arises when the coupling of a molecular network [inline-formula] to a downstream network [inline-formula] results in signal propagation back from [inline-formula] to [inline-formula].
Abhishek Deshpande, Thomas E. Ouldridge
doaj +1 more source
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
FEBS Letters, EarlyView.Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka +6 more
wiley +1 more source
Assessment of changes in clinical and biochemical indicators of saliva at caries according to monitoring [PDF]
Саратовский научно-медицинский журнал, 2013 The research goal was to determine the variability in the salivary characteristics, depending on the season, identifying the most important indicators of the salivary characteristics at different degrees of intensity of caries process and the ...
Albitskaya J.N. +6 more
doaj