Results 91 to 100 of about 508,313 (310)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Strategic Optimization of Nanoparticle Characteristics to Enhance Tumor Targeting and Doxorubicin Delivery

International Journal of Nanomedicine
Young-Jin Lee, Jisan Hong, Bo-Yeon Seo, Byung-Heon Lee, Vijaya Sarangthem,* Rang-Woon Park* Department of Biochemistry and Cell Biology, Cell & Matrix Research Institute, Kyungpook National University, School of Medicine, Daegu, 41944,
Lee YJ, Hong J, Seo BY, Lee BH, Sarangthem V, Park RW   +5 more
doaj  

Hematopoietic stem/progenitor cell transplantation recovers immune defects and prevents lymphomas in Atm-deficient mice

Experimental Hematology & Oncology
Background Ataxia-telangiectasia (A-T) is a rare autosomal recessive multi-system and life-shortening disease, characterized by progressive cerebellar neurodegeneration, immunodeficiency, radiation sensitivity and cancer predisposition, with high ...
Bruna Sabino Pinho de Oliveira, Alessandro Giovinazzo, Sabrina Putti, Matilde Merolle, Tiziana Orsini, Giuseppe D. Tocchini-Valentini, Christophe Lancrin, Fabio Naro, Manuela Pellegrini   +8 more
doaj   +1 more source

SAPK10-Mediated Phosphorylation on WRKY72 Releases Its Suppression on Jasmonic Acid Biosynthesis and Bacterial Blight Resistance

iScience, 2019
Summary: Bacterial blight caused by the infection of Xanthomonas oryzae pv. oryzae (Xoo) is a devastating disease that severely challenges the yield of rice. Here, we report the identification of a “SAPK10-WRKY72-AOS1” module, through which Xoo infection
Yuxuan Hou, Yifeng Wang, Liqun Tang, Xiaohong Tong, Ling Wang, Lianmeng Liu, Shiwen Huang, Jian Zhang   +7 more
doaj   +1 more source

The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms [PDF]

, 2008
© 2008 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,.
Sakwa, I, Höfken, T, Just, U, Tiedje, C
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Experimental Biology & Communication

, 2023
This introductory biology laboratory course covers the application of experimental techniques in microbiology, biochemistry, cell and developmental biology.
Steiner, Lisa, Guarente, Leonard, RajBhandary, Uttam, King, Jonathan   +3 more
core   +1 more source

Impact of Completion of a Pre-Pharmacy Biochemistry Course and Competency Levels in Pre-Pharmacy Courses on Pharmacy Student Performance

Pharmacy, 2019
Poor performance in foundational science courses, which are usually taken during the first or second year of pharmacy school, can have several negative consequences including increases in student drop-out rates and increases in the number of dismissals ...
Ruth Vinall, Parto Khansari, Jason McDowell, L. Douglas Ried, Eugene Kreys   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source