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Biochemistry and Biology of the Langerhans Cell
Hematology/Oncology Clinics of North America, 1987Langerhans cells mainly present in the normal epidermis and are thought to be identical to the proliferating cells in the lesions of histiocytosis-X. The Langerhans cell is positive not only for ATPase, esterase, and acid phosphatase, but also for S-100 protein.
Shaw Watanabe, Eiichi Ishii
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Biology and Biochemistry of Metastatic Cells [PDF]
There have been remarkable and continuing advances in the techniques for the diagnosis and treatment of primary neoplasms; however, the growth of tumor cells in organs distant to the primary tumor remains responsible for most deaths from cancer. Conventional therapy may be effective when primary neoplasms are detected before metastasis has occurred ...
Lance A. Liotta+2 more
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Cell Biology and Matrix Biochemistry of Chondromyxoid Fibroma [PDF]
We studied matrix composition and gene expression pattern in chondromyxoid fibromas on the protein and the messenger RNA levels. We could clearly identify focal chondrocytic differentiation within chondromyxoid fibroma by the expression and deposition of type II collagen, which is a marker of chondrocytic cell differentiation. We also were able to show
Stephan Söder+4 more
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The biochemistry and cell biology of aging: metabolic regulation through mitochondrial signaling.
American Journal of Physiology. Endocrinology and Metabolism, 2014Cellular and organ metabolism affects organismal lifespan. Aging is characterized by increased risks for metabolic disorders, with age-associated degenerative diseases exhibiting varying degrees of mitochondrial dysfunction.
Y. C. Long, T. Tan, Inoue Takao, B. Tang
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Retinal Biochemistry, Physiology and Cell Biology
2010The vitreous, the vasculature of the retina, macular pigments, phototransduction, retinal pigment epithelium, Bruch's membrane and the extracellular matrix, all play an important role in the normal function of the retina as well as in diseases. Understanding the pathophysiology allows us to target treatment.
Ricardo Luiz Smith+2 more
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Biochemistry, cell biology and molecular biology of lipids ofSaccharomyces cerevisiae [PDF]
The yeast Saccharomyces cerevisiae is a powerful experimental system to study biochemical, cell biological and molecular biological aspects of lipid synthesis. Most but not all genes encoding enzymes involved in fatty acid, phospholipid, sterol or sphingolipid biosynthesis of this unicellular eukaryote have been cloned, and many gene products have been
Günther Daum+3 more
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Matrix biochemistry and cell biology of dedifferentiated chondrosarcomas
Pathology International, 2010Dedifferentiated chondrosarcoma is an uncommon mesenchymal neoplasm comprised of two different components, low‐grade conventional chondrosarcoma and high‐grade non‐cartilaginous sarcoma. In order to gain better insight into the biology of this tumor, we investigated a large series of dedifferentiated chondrosarcomas by looking at the composition of the
Dornauer, K.+4 more
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Biochemistry and molecular cell biology of diabetic complications [PDF]
Diabetes-specific microvascular disease is a leading cause of blindness, renal failure and nerve damage, and diabetes-accelerated atherosclerosis leads to increased risk of myocardial infarction, stroke and limb amputation. Four main molecular mechanisms have been implicated in glucose-mediated vascular damage.
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Biological chemistry, 1998
Protein folding is a hierarchical process, driven by the accumulation of increments of free energy from local interactions between neighboring residues, secondary structural elements, domains and subunits.
R. Jaenicke
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Protein folding is a hierarchical process, driven by the accumulation of increments of free energy from local interactions between neighboring residues, secondary structural elements, domains and subunits.
R. Jaenicke
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