Results 21 to 30 of about 508,313 (310)
Corrigendum to “Effects of therapeutic hypothermia on the gut microbiota and metabolome of infants suffering hypoxic-ischemic encephalopathy at birth” [Int. J. Biochem. Cell Biol. 93 (December) (2017), 110-118] [PDF]
, 2019 peer-reviewedCorrigendum Refers to: Watkins, C., Murphy, K., Yen, S., Carafa, I., Dempsey, E., O’Shea, C., Vercoe, E., Ross, R., Stanton, C. and Ryan, C. (2017).
Ryan, Cornelius A. +9 more
core +1 more source
Nature Communications, 2023 The MUC2 mucin is a large, highly glycosylated polymer that builds the intestinal mucus. Here, the authors generate a high-resolution structural model of the 800 amino acid C-terminal dimer including its glycans.
Pablo Gallego +5 more
doaj +1 more source
A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
Nature Communications, 2016 The Piwi-interacting RNA (piRNA) pathway is known to suppress transposable elements in gonadal tissues. Here the authors provide evidence for a functional piRNA pathway in the somatic cells of theDrosophilafat body with roles in metabolism, immunological
Brian C. Jones +6 more
doaj +1 more source
SH3 domain-containing protein 2 Plays a Crucial Role at the Step of Membrane Tubulation during Cell Plate Formation [PDF]
, 2017 During cytokinesis in plants, trans-Golgi network-derived vesicles accumulate at the center of dividing cells and undergo various structural changes to give rise to the planar cell plate. However, how this conversion occurs at the molecular level remains
Stahelin, Robert V. +31 more
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Respiratory Research, 2022 Background Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature infants that may cause long-term lung dysfunction. Accumulating evidence supports the vascular hypothesis of BPD, in which lung endothelial cell dysfunction drives this ...
Jason L. Chang +7 more
doaj +1 more source
Detection of Extracellular Vesicle RNA Using Molecular Beacons
iScience, 2020 Summary: Extracellular vesicles (EVs) have recently emerged as intercellular conveyors of biological information and disease biomarkers. Identification and characterization of RNA species in single EVs are currently challenging.
Getulio Pereira de Oliveira, Jr. +9 more
doaj +1 more source
Cancer immunotherapy with T-cell targeting cytokines: IL-2 and IL-7
, 2021 Clinical trials have demonstrated that an increased number of effector cells, especially tumor-specific T cells, is positively linked with patients' prognosis. Although the discovery of checkpoint inhibitors (CPIs) has led to encouraging progress in
Seung-Woo Lee, 김지혜, 이건주
core +1 more source
Molecular Systems Biology, 2010 Systems biology can offer a great deal of insight into evolution by quantitatively linking complex properties such as protein structure, folding, and function to the fitness of an organism.
Matthew I Peña +4 more
doaj +1 more source
Role of Retinoic Acid Receptor-γ in DNA Damage-Induced Necroptosis
iScience, 2019 Summary: DNA-damaging compounds, commonly used as chemotherapeutic drugs, are known to trigger cells to undergo programmed cell death such as apoptosis and necroptosis.
Chamila Kadigamuwa +6 more
doaj +1 more source
Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome
, 2018 Thousands of cis-elements in genomes are predicted to have vital functions. Although conservation, activity in surrogate assays, polymorphisms, and disease mutations provide functional clues, deletion from endogenous loci constitutes the gold-standard ...
Rajendran Sanalkumar +11 more
core +1 more source