Results 111 to 120 of about 552,503 (299)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Evaluation of antimicrobial potential of free gallic acid and its polyvinyl-based nano-formulation
Scientific ReportsThis study explores the antimicrobial potential of gallic acid (GA) and gallic acid loaded with polyvinyl alcohol (PVA) nanocarriers as a good source of phenolic acids against various gram-positive bacteria including Staphylococcus aureus and ...
Habiba A. Ahmed +3 more
doaj +1 more source
Frontiers in Physiology, 2018 The non-reducing disaccharide trehalose is widely distributed among various organisms. It plays a crucial role as an instant source of energy, being the major blood sugar in insects. In addition, it helps countering abiotic stresses.
Bin Tang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Statistical Procedures for Finding Distribution Fits over Datasets with Applications in Biochemistry [PDF]
Bioautomation, 2009 A common problem in statistics is finding a distribution that fits to a certain dataset. Many theoretical distributions have been developed to give a good description of the empirical observations, and consequently, theory offers a variety of algorithms ...
Daniela S. Toneva +2 more
doaj
DNA Computing by Self-Assembly [PDF]
, 2003 Information and algorithms appear to be central to biological organization and processes, from the storage and reproduction of genetic information to the control of developmental processes to the sophisticated computations performed by the nervous ...
Winfree, Erik
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Performance of immobilized bacterial alpha-amylases in methyltriethoxsilane / tetraetoxysilane sol-gel matrices [PDF]
, 2007 The large number of studies related to the field of biomolecules encapsulation in sol-gel hosts clearly indicates that this approach can be considered as a powerful alternative to traditional encapsulation procedures involving biopolymer hosts.
Dudás, Zoltán Imre +2 more
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Characterization of thermophilic β-Glucosidase of rhizospheric bacterial strain (LSKB15) isolated from Cholistan Desert, Pakistan [PDF]
, 2018 Fifty thermophilic bacterial strains isolated from rhizospheric soil of Cholistan desert, Pakistan, and designated as LSKB01-LSKB50 were screened for β-glucosidase gene (bgl) belonging to glycoside hydrolase family 1 (GH 1) using PCR technique ...
Ahmed, Amer +4 more
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