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The medical biochemistry of poverty and neglect. [PDF]

Mol Med, 2014
Peter Hotez discusses his work on neglected tropical diseases and the future direction of disease elimination and science diplomacy. Published in the journal Molecular Medicine, December 2014.
Hotez PJ.
europepmc   +4 more sources

Medical Biochemistry as subdiscipline of laboratory medicine in Serbia [PDF]

Journal of Medical Biochemistry, 2017
Medical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia, and medical biochemist is the official name for the clinical chemist (or clinical biochemist). This is the largest sub-discipline of the laboratory medicine
Jovičić Snežana, Majkić-Singh Nada, Majkić-Singh Nada   +2 more
doaj   +2 more sources

Enhancing Learning in Medical Biochemistry by Teaching Based on VARK Learning Style for Medical Students [PDF]

Advances in Medical Education and Practice
Dutsadee Chinnapun, Udomsak Narkkul School of Medicine, Walailak University, Tha sala, Nakhon Si Thammarat, ThailandCorrespondence: Dutsadee Chinnapun, Email dutsadee-c@hotmail.comPurpose: Learners, including medical students, naturally have different ...
Chinnapun D, Narkkul U
doaj   +2 more sources

Quantitative Application of Sigma Metrics in Medical Biochemistry [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Laboratory errors are result of a poorly designed quality system in the laboratory. Six Sigma is an error reduction methodology that has been successfully applied at Motorola and General Electric. Sigma (σ) is the mathematical symbol for
Sunil Kumar Nanda, Lopamudra Ray
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Essentials of medical biochemistry: With clinical cases

Indian J Med Res, 2017
Kailashiya J, Mukherjee A, Dash D.
europepmc   +2 more sources

Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei

iScience, 2021
Summary: Extended synaptotagmins (E-Syts) localize at membrane contact sites between the endoplasmic reticulum (ER) and the plasma membrane to mediate inter-membrane lipid transfer and control plasma membrane lipid homeostasis.
Emma Stepinac, Nicolas Landrein, Daria Skwarzyńska, Patrycja Wójcik, Johannes Lesigang, Iva Lučić, Cynthia Y. He, Mélanie Bonhivers, Derrick R. Robinson, Gang Dong   +9 more
doaj   +1 more source

Side-by-side comparison of G-quadruplex (G4) capture efficiency of the antibody BG4 versus the small-molecule ligands TASQs

iScience, 2023
Summary: The search for G-quadruplex (G4)-forming sequences across the genome is motivated by their involvement in key cellular processes and their putative roles in dysregulations underlying human genetic diseases.
Yilong Feng, Zexue He, Zhenyu Luo, Francesco Rota Sperti, Ibai E. Valverde, Wenli Zhang, David Monchaud   +6 more
doaj   +1 more source

Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa

iScience, 2023
Summary: Hidradenitis suppurativa (HS) is a skin disorder that causes chronic painful inflammation and hyperproliferation, often with the comorbidity of invasive keratoacanthoma (KA).
Lin Jin, Mahendra P. Kashyap, Yunjia Chen, Jasim Khan, Yuanyuan Guo, Jari Q. Chen, Madison B. Lee, Zhiping Weng, Allen Oak, Prasanth Patcha, Tiffany Mayo, Rajesh Sinha, Venkatram Atigadda, Shahid M. Mukhtar, Jessy S. Deshane, Chander Raman, Carly Elston, Boni E. Elewski, Craig A. Elmets, Mohammad Athar   +19 more
doaj   +1 more source

SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis

iScience, 2022
Summary: SHP2 is the first oncogenic tyrosine phosphatase encoded by PTPN11, which plays a significant regulatory role in cancer and inflammation-related diseases. Although SHP2 allosteric inhibitors have been used in phase I/II clinical trials for solid
Meijing Wang, Tinghan Li, Zijun Ouyang, Kai Tang, Yuyu Zhu, Chenglin Song, Haiyan Sun, Bin Yu, Xiaoyun Ji, Yang Sun   +9 more
doaj   +1 more source

Identification and characterization of andalusicin: N-terminally dimethylated class III lantibiotic from Bacillus thuringiensis sv. andalousiensis

iScience, 2021
Summary: Lanthipeptides, ribosomally synthesized and post-translationally modified peptides (RiPPs), can be divided into five classes based on their structures and biosynthetic pathways. Class I and II lanthipeptides have been well characterized, whereas
Anastasiia Grigoreva, Julia Andreeva, Dmitry Bikmetov, Anastasiia Rusanova, Marina Serebryakova, Andrea Hernandez Garcia, Darya Slonova, Satish K. Nair, Guy Lippens, Konstantin Severinov, Svetlana Dubiley   +10 more
doaj   +1 more source