Results 31 to 40 of about 580,532 (253)

A novel APA-based prognostic signature may predict the prognosis of lung adenocarcinoma in an East Asian population

iScience, 2023
Summary: The role of alternative polyadenylation (APA) in tumor development is becoming increasingly evident, but the impact of APA events on the prognosis of LUAD patients is unclear.
Wendi Zhang, Yang Hu, Min Qian, Liping Mao, Yanqiong Yuan, Huiwen Xu, Yiran Liu, Anni Qiu, Yan Zhou, Yang Dong, Yutong Wu, Qiong Chen, Xiaobo Tao, Tian Tian, Lei Zhang, Jiahua Cui, Minjie Chu   +16 more
doaj   +1 more source

Biochemometry identifies ostruthin as pluripotent antimicrobial and anthelmintic agent from masterwort

iScience, 2023
Summary: The root extract of Peucedanum ostruthium (PO-E) was identified as a promising antibacterial source from a screening of 158 extracts against Staphylococcus aureus.
Julia Zwirchmayr, Cristina D. Cruz, Ulrike Grienke, Päivi Tammela, Judith M. Rollinger   +4 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Chemical and biological characterization of vaccine adjuvant QS-21 produced via plant cell culture

iScience
Summary: Many vaccines, including those using recombinant antigen subunits, rely on adjuvant(s) to enhance the efficacy of the host immune responses. Among the few adjuvants clinically approved, QS-21, a saponin-based immunomodulatory molecule isolated ...
Xiangmin Lv, Jesse Martin, Heather Hoover, Bishnu Joshi, Margaret Wilkens, David A. Ullisch, Thomas Leibold, John S. Juchum, Sanket Revadkar, Barbara Kalinovska, Justin Keith, Adam Truby, Gui Liu, Elaine Sun, John Haserick, Jon DeGnore, Joseph Conolly, Adrian V.S. Hill, John Baldoni, Charlotte Kensil, Dan Levey, Alexandra J. Spencer, Gilbert Gorr, Mark Findeis, Antoine Tanne   +24 more
doaj   +1 more source

Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP‐WT‐2001 Protocol in the SIOP‐UK‐CCLG and SIOP‐GPOH Studies (2001–2022)

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić, Rhoikos Furtwängler, Tanzina Chowdhury, Christian Vokuhl, Jenny Wegert, Norbert Graf   +5 more
wiley   +1 more source

Biochemistry for Medical Students [PDF]

Nature, 1955
Biochemistry By Prof. Abraham Cantarow and Dr. Bernard Schepartz. Pp. xxv + 848. (Philadelphia and London: W. B. Saunders Company, 1954.) 55s.
openaire   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Hair metal dysregulation in Parkinson’s disease: Implications for diagnosis and gut-brain axis involvement

iScience
Summary: This study investigated hair metals as potential biomarkers in Parkinson’s disease (PD) and their link to gut-mediated iron metabolism. In 60 PD patients and matched controls, hair analysis revealed a distinct profile: significantly lower iron ...
Ming Li, Ying Li, Yixian Li, Chenchen Zhang, Fan Lu, Linli Liu, Hongjie Wang, Li Ling, Jiguang Guo   +8 more
doaj   +1 more source

Correction to: Comparing Serum Zinc and Cortisol Concentrations in Patients with Major Depressive Disorder Treated with Fluoxetine and Cognitive-Behavioral Therapy: A Randomized Clinical Trial [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Mehrdad Jalalian1, Mehdi Pourasghar2, Ahmad Majd3, Hossein Ghalehnoei4, Zahra Kianmehr5 1 PhD Student in Biochemistry, Department of Biochemistry, Faculty of Biological Sciences, North Tehran Branch, Islamic Azad University, Tehran, Iran 2 Associate
Mehrdad Jalalian, Mehdi Pourasghar, Ahmad Majd, Hossein Ghalehnoei, Zahra Kianmehr   +4 more
doaj