Results 131 to 140 of about 164,527 (299)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Recent developments in applied microbiology and biochemistry /
"Touching all areas of microbiology, Recent Developments in Applied Microbiology and Biochemistry provides understanding to the application-oriented microbial concepts and updates the knowledge with recent developments on related aspects of both ...
Viswanath, Buddolla,editor.
core
Evaluation of ebony as a potential selectable marker for genetic sexing in Aedes aegypti
Parasites & VectorsBackground Aedes aegypti is expected to invade previously unoccupied areas, mainly due to the climate change, the increase in travel and trade activities and the continuous transformation of the rural environment into urban areas.
Katerina Nikolouli +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
High-solids anaerobic digestion: process biochemistry and optimization
, 2017 High-solids anaerobic digestion: process biochemistry and optimization. 1.
Pastor-Poquet, V. +3 more
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Scientific ReportsThis study focuses on the sustainable extraction of chitosan from shrimp shell waste and its application in developing frankincense-loaded chitosan nanoparticles with enhanced antimicrobial efficacy. Chitosan was extracted through demineralization with 4%
Habiba A. Ahmed +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The Local Minimum Dataset of Biochemistry Laboratory Information Systems
مدیریت اطلاعات سلامت, 2016 Introduction: Biochemistry laboratories provide important information about the health status of people for clinical interventions and decisions. The purpose of this study was to evaluate the data elements of biochemistry laboratory information systems ...
Mehrnoosh Shahmoradi +2 more
doaj