Results 31 to 40 of about 153,506 (256)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Differential increase in endocannabinoid levels at the plasma and intracellular membranes

iScience
Summary: Endocannabinoids (eCBs) modulate the activity of proteins expressed at the plasma and intracellular membranes. Nothing is known about the dynamic changes in eCB levels in these subcellular compartments.
Simar Singh, Anthony English, Jackson Yu, Dennis Sarroza, Larry Zweifel, Michael R. Bruchas, Benjamin B. Land, Oscar Vivas, Nephi Stella   +8 more
doaj   +1 more source

Feather protein lysate optimization and feather meal formation using YNDH protease with keratinolytic activity afterward enzyme partial purification and characterization

Scientific Reports, 2021
Incubation parameters used for the creation of a protein lysate from enzymatically degraded waste feathers using crude keratinase produced by the Laceyella sacchari strain YNDH were optimized using the Response Surface Methodology (RSM); amino acids ...
Doaa A. Goda, Ahmad R. Bassiouny, Nihad M. Abdel Monem, Nadia A. Soliman, Yasser R. Abdel-Fattah   +4 more
doaj   +1 more source

Investigation of a Structured Fisher's Equation with Applications in Biochemistry [PDF]

SIAM Journal on Applied Mathematics, 2018
Recent biological research has sought to understand how biochemical signaling pathways, such as the mitogen-activated protein kinase (MAPK) family, influence the migration of a population of cells during wound healing. Fisher's Equation has been used extensively to model experimental wound healing assays due to its simple nature and known traveling ...
John T. Nardini, David M. Bortz
openaire   +4 more sources

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Phosphorus Flame Retardants for Polymeric Materials from Gallic Acid and Other Naturally Occurring Multihydroxybenzoic Acids

International Journal of Polymer Science, 2018
The development of polymer and polymer additives from renewable biosources is becoming increasingly prominent. This reflects increasing concerns about sustainability, environmental quality, and human health.
Bob A. Howell, Kendahl L. Oberdorfer, Eric A. Ostrander   +2 more
doaj   +1 more source

New Methods for Synthesizing DNA, RNA, and Phosphonates

CHIMIA, 2005
The development of new methods for the synthesis of DNA, RNA, and phosphonates has enabled new applications in biochemistry and biology.
Marvin H. Caruthers
doaj   +1 more source

Photochemical spin-state control of binding configuration for tailoring organic color center emission in carbon nanotubes

Nature Communications, 2022
Chemical functionalization of the sidewalls of single-wall carbon nanotubes (SWCNTs) is an emerging route to introduce fluorescent quantum defects and tailor the emission properties.
Yu Zheng, Yulun Han, Braden M. Weight, Zhiwei Lin, Brendan J. Gifford, Ming Zheng, Dmitri Kilin, Svetlana Kilina, Stephen K. Doorn, Han Htoon, Sergei Tretiak   +10 more
doaj   +1 more source

Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP‐WT‐2001 Protocol in the SIOP‐UK‐CCLG and SIOP‐GPOH Studies (2001–2022)

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić, Rhoikos Furtwängler, Tanzina Chowdhury, Christian Vokuhl, Jenny Wegert, Norbert Graf   +5 more
wiley   +1 more source

exoCasMINI: A T5 exonuclease fused CRISPR-Cas12f system with enhanced gene editing efficiency

iScience
Summary: CRISPR-Cas9 and Cas12a are widely used for genome editing, but their large size limits delivery efficiency. Compact Cas12f proteins offer delivery advantages but suffer from low activity.
Kaitong Liao, Kechen Chen, Shufeng Ma, Xiaofeng Yang, Peihan Chen, Sijie Li, Mengrao Li, Xin Zhang, Ying Lin   +8 more
doaj   +1 more source